Terson综合征的发病机制

Pathogenesis of Terson syndrome

Terson综合征是颅内出血引起的眼内出血,在蛛网膜下腔出血的患者中尤为常见。目前Terson综合征具体发病机制暂不明确,可能的发病机制有:颅内出血导致颅内压增高,增高的颅内压引起视网膜静脉回流受阻,引起静脉阻塞性出血;颅内出血沿视神经鞘进入眼内,引起眼内出血。近来从颅内到眼球的类淋巴系统成为该疾病新的研究方向,为Terson综合征的发病机制提供另外一种可能,并有可能为其他眼科疾病提供一种新的思路。

Terson syndrome is an intraocular hemorrhage caused by intracranial hemorrhage,which is particularly common in patients with subarachnoid hemorrhage.At present,the specific pathogenesis of Terson syndrome is not clear,but the current mainstream pathogenesis is as follows:first,intracranial hemorrhage leads to increased intracranial pressure,and increased intracranial pressure leads to blocked retinal venous reflux,resulting in venous obstructive bleeding;the other is intracranial hemorrhage along the optic nerve sheath into the eye,causing intraocular hemorrhage.Recently,the lymphatic system from the intracranial to the eyeball has become a new research direction of this disease,providing another possibility for the pathogenesis of Terson syndrome and possibly a new way of thinking for other ophthalmic diseases.