基于Au@Co-MOF/GCE传感器检测阿魏酸的研究

Determination of ferulic acid based on Au@Co-MOF/GCE sensor

合成了钴金属有机骨架(Cobalt metal organic skeleton,Co-MOF)纳米材料并在此基础上负载金纳米粒子(Gold nanomaterials,Au)制备了一种新型的金@钴金属有机骨架(Gold@Cobalt metal organic skeleton Nanocomposites,Au@Co-MOF)纳米复合材料。以Au@Co-MOF为修饰材料,采用玻碳电极(Glassy carbon electrode,GCE)为工作电极,构建Au@Co-MOF/GCE。通过对磷酸盐缓冲溶液(Phosphate buffer solution,PBS)和Au@Co-MOF的优化,确定了Au@Co-MOF/GCE的最佳工作条件。研究发现,阿魏酸浓度与其氧化峰电流分别在0.05~4 μmol/L和4~450 μmol/L范围内呈现线性关系,检出限(S/N=3)为0.0089 μmol/L,明显优于其它传感器且Au@Co-MOF/GCE抗干扰能力、重复性和稳定性良好,30 d后其对阿魏酸的检测结果仍可达到最初的95.04%,连续8次检测结果的RSD为3.05%。Au@Co-MOF/GCE操作简单、检出限低、灵敏度高可用于阿魏酸的快速定量分析。

Cobalt metal organic skeleton(Co-MOF)nanomaterials were synthesized and Gold nanomaterials(Au)were loaded on Co-MOF for preparing a new Au@Co-MOF nanocomposites. The Au@Co-MOF/GCE sensor was prepared using glassy carbon electrode(GCE)as working electrode and Au@Co-MOF as the modified material. The best working conditions of Au@Co-MOF/GCE was determined by optimizing phosphate buffer solution(PBS)and Au@Co-MOF. The results showed that there was a good linear relationship between ferulic acid concentration and oxidation peak current in the range of 0.05~4 μmol/L and 4~450 μmol/L,respectively. The detection limit(S/N=3)was 0.0089 μmol/L and much better than other electrochemical sensors. Au@Co-MOF/GCE had good anti-interference ability,repeatability and stability. After 30 days,the detection result of ferulic acid could still reach the initial 95.04%,and RSD of 8 consecutive detection results was 3.05%. Au@Co-MOF/GCE had advantages of simple operation,low detection limit and high sensitivity,and could be used for rapid detecting of ferulic acid.