补充维生素D乳清蛋白及抗阻运动对老年肌肉衰减综合征营养状态和健康水平的影响

Effects of Vitamin D Supplementation Lactoalbumin Supplementation and Resistance Exercise on Nutritional Status and Health Level in Elderly Patients with Sarcopenia Syndrome

目的:探讨补充维生素D、乳清蛋白及抗阻运动对老年肌肉衰减综合征营养状态和健康水平的影响。方法:选取我院2020年1月至2022年1月收治的150例老年肌肉衰减综合征患者作为研究对象,按照随机数字表法将研究对象简单随机分为对照组和观察组各75例,对照组予常规健康宣教及普通膳食干预,观察组予补充维生素D、乳清蛋白及抗阻运动干预,为期6个月。观察两组干预前后营养指标、上下肢肌力、肌肉质量变化、肌肉功能、肢体运动功能情况及健康水平。结果:干预6个月后,两组患者血清总蛋白、前白蛋白及白蛋白水平均高于干预前,且观察组血清总蛋白、前白蛋白及白蛋白干预前后差值大于对照组(P<0.05);两组患者伸膝肌力、屈轴肌力及肌肉质量均高于干预前,且观察组患者伸膝肌力、屈轴肌力、肌肉质量干预前后差值均高于对照组(均P<0.05);观察组肌肉功能(优49例,中24例,差2例)优于对照组(优31例,中35例,差9例)(P<0.05);两组简易上肢功能评价工具(STEF)及Berg平衡量表(BBS)评分均高于干预前,且观察组STEF量表及BBS量表评分干预前后差值高于对照组(均P<0.05);两组生理健康、心理健康及社会健康评分均高于干预前,且观察组各评分干预前后差值高于对照组(均P<0.05)。结论:补充维生素D、乳清蛋白及抗阻运动可有效改善老年肌肉衰减综合征患者营养状态,并增强患者肌力、改善肌肉质量和肌肉功能,促进患者肢体运动功能恢复,改善患者整体健康状态。

Objective:To investigate the effects of vitamin D and lactoalbumin supplementations and resistance exercise on nutritional status and health level of elderly sarcopenia syndrome.Methods:150 elderly patients with sarcopenia syndrome who were treated in the hospital from January 2020 to January 2022 were selected as the study subjects.According to the random number table method,the study subjects were divided into control group(75 cases)and observation group(75 cases)by the simple randomization.The control group received routine health education and ordinary diet intervention while the observation group was given vitamin D supplementation,lactoalbumin supplementation and resistance exercise intervention,and they were treated for 6 months.The nutritional indicators,upper and lower limb muscle strengths,muscle mass,muscle function,limb motor function and health level were observed before and after intervention in the two groups.Results:After 6 months of intervention,the levels of serum total protein,prealbumin and albumin in both groups were higher than those before intervention,and the differences of the above indicators before and after intervention in observation group were greater than those in control group(P<0.05).The knee extension muscle strength,flexion muscle strength and muscle mass in the two groups of patients were higher than those before intervention,and the differences of the above three indicators before and after intervention were higher in observation group than those in control group(all P<0.05).The muscle function grades in observation group(excellent in 49 cases,medium in 24 cases,poor in 2 cases)were better than those in control group(excellent in 31 cases,medium in 35 cases,poor in 9 cases)(P<0.05).The scores of simple test for evaluating hand function(STEF)and Berg balance scale(BBS)in both groups were higher than those before intervention,and the differences of STEF score and BBS score before and after intervention in observation group were higher than those in control group(all P<0.05).The scores of physical health,psychological health and social health in the two groups were higher than those before intervention,and the differences of the above scores before and after intervention were higher in observation group compared to control group(all P<0.05).Conclusion:Supplementations of vitamin D and lactoalbumin and resistance exercise can effectively improve the nutritional status,enhance the muscle strength,improve the muscle mass and muscle function,promote the recovery of limb motor function,and improve the overall health status of elderly patients with sarcopenia syndrome.