帕金森病患者围手术期的药物治疗管理

Perioperative Management of Drug Therapy for Patients with Parkinson's Disease

帕金森病(PD)是一种常见的神经退行性疾病。近年来接受手术的PD患者越来越多,而PD症状对手术有重要影响,且在术前突然停用或减少抗PD药物可能导致产生严重的并发症,使PD患者的手术风险增加。此外,围手术期常用的其他药物也可能对PD症状产生影响或者与抗PD药物存在不良相互作用。鉴于上述原因,PD患者围手术期的药物治疗管理显得尤为重要。然而,PD围手术期的药物治疗管理目前仍缺乏统一的标准。因此,该文就PD患者围手术期的药物治疗管理作一综述,内容主要包括抗PD药物管理、围手术期常用药物管理及药学监护,以期为PD患者围手术期临床药物治疗提供参考,减少术后并发症。

Parkinson's disease(PD)is a common neurodegenerative disorder.In recent years,there are more and more surgeries for PD patients,while PD symptom has an important influence on surgery.In addition,sudden withdrawal or reduction of anti-PD drugs before surgery may lead to serious complications,increasing the risk of surgery for PD patients.On the other hand,other commonly used perioperative drugs may also affect PD symptoms or have adverse interactions with anti-PD drugs.In view of the above reasons,perioperative drug therapy management of PD patients is particularly important.However,there is still a lack of unified standards for perioperative drug management of PD.Therefore,in order to provide references for perioperative clinical drug therapy for PD patients and reduce postoperative complications,this paper reviews perioperative drug therapy management for PD patients,mainly including anti-PD drug management,perioperative management of common drugs,and pharmaceutical care.