代谢相关脂肪性肝病:慢性肾脏病的一个启动因素

Metabolic-associated fatty liver disease as a driver of chronic kidney disease

代谢相关脂肪性肝病(MAFLD)原名非酒精性脂肪肝(NAFLD),是发达国家慢性肝病最常见的病因,在发展中国家发病率也不断增加。NAFLD更名为MAFLD是脂肪性肝病诊疗领域一个新突破,有利于疾病早期预防和干预。慢性肾脏病(CKD)是威胁人类健康的常见慢性疾病之一,而代谢功能紊乱(高血压、糖尿病)正成为CKD的主要病因。将MAFLD与CKD的发生和进展联系起来的证据正在成为科学研究的热门领域。本文就MAFLD和CKD之间的关系研究作一综述。

Metabolic-associated fatty liver disease(MAFLD),formerly known as nonalcoholic fatty liver disease(NAFLD),is the most common cause of chronic liver disease in developed countries,and its incidence is also increasing in developing countries.NAFLD renamed MAFLD is a new breakthrough in the diagnosis and management of fatty liver disease,which is beneficial to the early prevention and intervention of the disease.Chronic kidney disease(CKD)is one of the common chronic diseases that threaten human health,and metabolic dysfunction(hypertension,diabetes mellitus)is becoming the main cause of CKD.Evidence linking MAFLD to the development and progression of chronic kidney disease(CKD)is becoming a hot area of scientific research.This paper summarizes the research on the relationship between MAFLD and CKD.