血管腔内成形术治疗下肢动脉硬化闭塞症的临床疗效分析

Clinical Efficacy Analysis of Endoluminal Angioplasty for Lower Limb Atherosclerotic Occlusive Disease

目的 分析在下肢动脉硬化闭塞症(arteriosclerosis obliterans, ASO)治疗中,采取血管腔内成形术干预的临床价值。方法 方便选取2019年9月—2021年9月间三明市第二医院收治的86例下肢动脉硬化闭塞症患者为研究对象,采取随机数表法将其分为两组,各43例。对照组实施非手术治疗干预,观察组则实施腔内血管成形术干预;对比观察在不同治疗方案下两组患者的康复效果、踝肱指数(ABI)、间歇性跛行距离、疼痛程度及血流动力学指标(血流峰速、血流量以及血管内径)。结果 观察组治疗总有效率高于对照组(95.35%vs 79.07%),差异有统计学意义(χ^(2)=5.108,P=0.024)。观察组治疗后1、3个月的ABI指数高于对照组,差异有统计学意义(t=6.120、4.834,P<0.05);且观察组1、3个月的间歇性跛行距离长于对照组,差异有统计学意义(t=9.128、6.817,P<0.05)。治疗,观察组治疗后1、3个月疼痛程度均低于对照组,差异有统计学意义(t=3.744、6.579,P<0.05)。观察组治疗后血流峰速、血流量以及血管内径分别为(46.88±5.46)cm/s、(35.89±3.45)mL/(s·m~2)、(1.35±0.34)mm,优于对照组的(39.35±5.34)cm/s、(27.25±3.60)mL/(s·m~2)、(0.83±0.30)mm,差异有统计学意义(t=6.465、11.363、7.520,P<0.05)。结论 在下肢动脉硬化闭塞症(ASO)治疗中,采取血管腔内成形术干预效果显著,可有助于改善患者血流动力学指标,提升其踝肱指数。

Objective To analyze the clinical value of intervention with endovascular lumpectomy in the treatment of arteriosclerosis obliterans(ASO).Methods A total of 86 patients with arteriosclerotic obliterans of lower limbs admitted to the Second Hospital of Sanming City from September 2019 to September 2021 were conveniently selected as the study objects.The patients were divided into two groups with 43 cases in each group by random number table method.The control group received non-surgical treatment intervention,and the observation group received endovascular an⁃gioplasty intervention.The rehabilitation effect,ankle-brachial index(ABI),intermittent claudicity distance,pain de⁃gree and hemodynamic parameters(peak velocity,blood flow and vascular diameter)were compared between the two groups under different treatment regiments.Results The total effective rate of observation group was higher than control group(95.35%vs 79.07%),the difference was statistically significant(χ^(2)=5.108,P=0.024).ABI index of observation group was higher than that of control group at 1 and 3 months after treatment,the difference was statistically signifi⁃cant(t=6.120,4.834,P<0.05).The distance of intermittent claudication in the observation group was longer than that in the control group at 1 and 3 months after treatment,and the difference was statistically significant(t=9.128,6.817,P<0.05).The pain degree of observation group was lower than the control group at 1 and 3 months after treatment,and the difference was statistically significant(t=3.744,6.579,P<0.05).The peak blood flow velocity,blood flow and vascular diameter of the observation group after treatment were(46.88±5.46)cm/s,(35.89±3.45)mL/(s·m2),(1.35±0.34)mm,respectively,were better than the control group(39.35±5.34)cm/s,(27.25±3.60)mL/(s·m2)and(0.83±0.30)mm,and the difference was statistically significant(t=6.465,11.363,7.520,P<0.05).Conclusion In the treatment of atherosclerosis-occlusive disease of the lower extremities(ASO),endovascular lumpectomy is effective and can help improve the hemodynamic index and ankle-brachial index of patients.