胰岛素强化治疗对糖尿病合并急性脑梗死的症状改善情况分析

Analysis of Improvement of Symptoms of Complicated with Intensive Insulin Treatment of Diabetes Mellitus

目的 探究胰岛素强化治疗糖尿病合并急性脑梗死的有效性。方法 选取2020年8月—2022年8月漳浦县医院收治的50例糖尿病合并急性脑梗死患者作为研究对象,以随机数表法分为两组,对照组接受常规治疗,观察组在对照组基础上接受胰岛素强化治疗,对比两组疗效。结果 观察组治疗总有效率为88.00%,明显高于对照组的60.00%,差异有统计学意义(χ^(2)=5.094,P<0.05);与治疗前比较,两组治疗后各项血糖指标水平均降低,且观察组低于对照组,差异有统计学意义(P<0.05);与治疗前比较,两组治疗后各项胰岛功能指标均有所改善,且观察组HOMA-β高于对照组,FINS、HOMA-IR低于对照组,差异有统计学意义(P<0.05);与治疗前比较,两组治疗后NIHSS评分均有所降低,且观察组低于对照组,差异有统计学意义(P<0.05)。结论 胰岛素强化治疗糖尿病合并急性脑梗死可有效改善患者的临床症状及神经功能缺损状况,实现对血糖水平的有效控制。

Objective To explore the effectiveness of insulin intensive treatment of diabetes mellitus complicated with acute cerebral infarction.Methods Fifty patients with diabetes mellitus complicated with acute cerebral infarction ad⁃mitted to Zhangpu County Hospital from August 2020 to August 2022 were selected as research objects and divided into two groups by random number table method.The control group received conventional treatment,and the observa⁃tion group received insulin intensive treatment on the basis of the control group.The efficacy of the two groups was compared.Results The total effective rate of the observation group was 88.00%,which was significantly higher than that of the control group(60.00%),and the difference was statistically significant(χ^(2)=5.094,P<0.05).Compared with before treatment,the levels of various blood glucose indexes in both groups were decreased after treatment,and the ob⁃servation group was lower than the control group,the difference was statistically significant(P<0.05).Compared with before treatment,the islet function indexes of the two groups were improved after treatment,HOMA-βof the observa⁃tion group was higher than that of the control group,FINS and HOMA-IR were lower than that of the control group,the difference was statistically significant(P<0.05).Compared with before treatment,NIHSS score in both groups de⁃creased after treatment,and observation group was lower than control group,the difference was statistically significant(P<0.05).Conclusion Insulin intensive treatment of diabetes mellitus complicated with acute cerebral infarction can effectively improve the clinical symptoms and neurological deficits of patients,and achieve effective control of blood glucose level.