摘要
隐丹参酮(CTS)作为一种高效低毒的天然化合物,在各器官组织中具有良好的抗纤维化作用,但目前其作用机制尚未明确,且无系统的文献综述对其抗纤维化潜在机制进行描述。笔者综述了隐丹参酮治疗各脏器纤维化的疗效及其机制,并提出了未来展望。
As a natural compound with high efficiency and low toxicity,cryptotanshinone(CTS)has a good anti-fibrosis effect in various organs and tissues.However,its mechanism of action has not been clearly defined,and there is no systematic literature review to describe its potential anti-fibrosis mechanism.The efficacy and mechanism of cryptotanshinone in the treatment of fibrosis in various organs were summarized and the use prospects were put forward in this paper.
作者
刘亚谊
张俊平
LIU Yayi;ZHANG Junping(School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China;School of Pharmacy,Naval Medical University,Shanghai 200433,China)
出处
《药学实践与服务》
CAS
2023年第3期146-148,186,共4页
Journal of Pharmaceutical Practice and Service
基金
福建中医药大学高层次人才科研启动资金项目(X2019005)。
关键词
隐丹参酮
肾纤维化
肺纤维化
心纤维化
肝纤维化
作用机制
cryptotanshinone
renal fibrosis
pulmonary fibrosis
cardiac fibrosis
liver fibrosis
mechanism
