药物联合认知行为治疗青少年伴非自杀性自伤抑郁症的效果观察

Effect Observation of Drugs Combined with Cognitive Behavioral Therapy in Adolescents with Non-Suicidal Self-Injury Depression

目的:探讨药物联合认知行为治疗青少年伴非自杀性自伤抑郁症的效果。方法:选取2021年1月—2022年3月徐州市东方人民医院收治的36例青少年伴非自杀性自伤抑郁症患者作为研究对象,按治疗方案不同分为对照组与研究组,各18例。对照组给予药物治疗,研究组在对照组基础上联合认知行为治疗。比较两组临床疗效、抑郁程度、应对方式评分、生活质量评分。结果:研究组治疗总有效率高于对照组,差异有统计学意义(P=0.035)。治疗前,两组汉密尔顿抑郁量表(HAMD)、蒙哥马利抑郁评定量表(MADRS)评分比较,差异无统计学意义(P>0.05);治疗后,研究组HAMD、MADRS评分低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组积极应对评分高于对照组,消极应对评分低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组各项生活质量评分均高于对照组,差异有统计学意义(P<0.05)。结论:药物联合认知行为治疗青少年伴非自杀性自伤抑郁症的效果显著,可明显改善患者抑郁程度、应对方式以及生活质量。

Objective:To explore the effect of drugs combined with cognitive behavioral therapy in adolescents with non-suicidal self-injury depression.Methods:From January 2021 to March 2022,a total of 36 adolescent patients with non-suicidal self-injury depression admitted to Xuzhou Oriental People's Hospital were selected as the study subjects.They were divided into control group and study group according to different treatment schemes,with 18 patients in each group.The control group was given drug treatment,and the study group was given cognitive behavioral therapy on the basis of control group.The clinical efficacy,depression degree,coping style score and quality of life score in the two groups were compared.Results:The total effective rate of treatment in the study group was higher than that in the control group,and the difference was statistically significant(P=0.035).Before treatment,there was no significant difference in the scores of Hamilton Depression Rating Scale(HAMD)and Montgomery-Asberg Depression Rating Scale(MADRS)between the two groups(P>0.05).After treatment,the HAMD and MADRS scores in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the positive coping score in the study group was higher than that in the control group,and the negative coping score in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the quality of life scores in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:The effect of drugs combined with cognitive behavioral therapy for adolescents with non-suicidal self-injury depression is significant,it can obviously improve the degree of depression,coping style and quality of life.