2016-2020年甘肃省人间布鲁氏菌病空间流行特征分析

Spatial epidemic characteristics of human brucellosis in Gansu Province from 2016 to 2020

目的了解甘肃省人间布鲁氏菌病(简称布病)疫情动态和空间流行特征。方法收集2016年1月至2020年12月中国疾病预防控制信息系统报告的甘肃省人间布病疫情资料,采用描述流行病学方法和空间聚集性分析方法对资料进行分析。结果2016-2020年甘肃省共报告人间布病10025例,年份间发病率比较差异有统计学意义(χ^(2)=242.86,P=0.001),2018年发病率最低(6.03/10万),2020年发病率最高(11.39/10万)。报告病例集中在45~55岁,占34.52%(3461/10025);男女性别比为2.91∶1.00(7458/2567);职业以农民为主,占82.11%(8232/10025)。全省86个县(市、区)中,报告病例数最高为2020年永昌县(339例),发病率最高为2020年肃南裕固族自治县(190.89/10万)。空间自相关分析显示,2016-2020年甘肃省人间布病发病率存在显著的空间正相关(全局莫兰指数均>0,均Z>1.96,均P<0.05),呈空间聚集性分布;高-高聚集的地区集中在永昌县、肃南裕固族自治县。结论甘肃省人间布病发病人群主要为中年男性农民,发病率呈空间聚集性分布。

Objective To learn about the epidemic dynamics and spatial epidemic characteristics of human brucellosis in Gansu Province.Methods Data on human brucellosis in Gansu Province reported by China Disease Control and Prevention Information System from January 2016 to December 2020 were collected and analyzed by descriptive epidemiology and spatial clustering analysis.Results A total of 10025 cases of human brucellosis were reported in Gansu Province from 2016 to 2020,with a statistically significant difference in incidence rate between years(χ^(2)=242.86,P=0.001).The incidence was the lowest in 2018(6.03/100000),and the highest in 2020(11.39/100000).The reported cases were concentrated in 45-55 years old,accounting for 34.52%(3461/10025);the male to female ratio was 2.91∶1.00(7458/2567);farmers were the main occupation,accounting for 82.11%(8232/10025).Among the 86 counties(cities,districts)in Gansu Province,Yongchang County had the highest number of reported cases in 2020(339 cases),and Sunan Yugur Autonomous County had the highest incidence in 2020(190.89/100000).Spatial autocorrelation analysis showed that there was significant spatial positive correlation between the incidence rate of human brucellosis in Gansu Province from 2016 to 2020(global Moran's I>0,Z>1.96,P<0.05),showing a spatial clustering distribution.The high-high clustering areas were concentrated in Yongchang County and Sunan Yugur Autonomous County.Conclusion In Gansu Province,the main population of human brucellosis is middle-aged male farmers,and the incidence of brucellosis is spatially clustered.