艾灸治疗脑卒中后尿失禁临床效果的Meta分析

Meta-analysis of the clinical efficacy of moxibustion for urinary incontinence after stroke

目的运用Meta分析评价艾灸治疗脑卒中后尿失禁的临床疗效。方法计算机检索国内外数据库中关于运用艾灸疗法干预脑卒中后尿失禁的随机对照试验。检索时间从建库至2021年3月。两位研究人员独立筛选文献、提取数据,并对纳入文献进行风险评估。采用RevMan5.3软件进行系统的评价分析。结果共纳入16篇随机对照试验,共计1024例患者。Meta分析结果显示:与常规治疗和护理方法相比,艾灸治疗可以安全有效地改善排尿日记相关指标(白天尿失禁次数、夜间护理人员被叫次数、平均尿量)、尿失禁临床症状评分和疗效评价,并且对患者的生活质量和日常生活能力均有积极影响,但艾灸疗程可能会对治疗效果造成影响。结论灸疗可能是治疗脑卒中后尿失禁的有效干预手段。但考虑到纳入研究数量、研究设计的方法质量有限,故分析得出的研究证据只能被视为初步证据。在今后的研究中仍需纳入更多高质量、大样本的随机双盲对照试验来增加证据的强度。

Objective To evaluate the clinical efficacy of moxibustion in the treatment of urinary incontinence after stroke using the method of Meta analysis.Methods Domestic and foreign databases by computer were searched for all randomized controlled trials related to moxibustion for urinary incontinence after stroke.The search time was from the establishment of the database to March 2021.Two researchers independently screened the literature,extracted data,and conducted risk assessment of the included literature.RevMan5.3 software was used for systematic evaluation and analysis.Results 16 randomized controlled trials were included in total,and the total number of patients included was 1024.Meta analysis results showed that compared with conventional treatments and nursing methods,moxibustion treatment can safely and effectively improve urinary diary related indicators(daytime urinary incontinence,night nursing staff calls,average urine output),urinary incontinence clinical symptom score and efficacy evaluation.And it had a positive impact on the patient′s quality of life and ability of daily living,but the course of moxibustion might affect the treatment effect.Conclusions Moxibustion might be an effective intervention for treating urinary incontinence after stroke.However,considering the limited number of included studies and quality of research design methods,the research evidence derived from this Meta analysis could only be regarded as preliminary evidence.In future studies,more high-quality,large-sample randomized double-blind controlled trials still need to be included to increase the strength of the evidence.