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心脑血管疾病瘀毒互结证的研究现状与展望 被引量:4

Research status and prospect of blood stasis and toxin syndrome in cardiovascular and cerebrovascular diseases
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摘要 瘀毒互结是心脑血管疾病的常见证型,也是疾病迁延和恶化的关键病机。笔者对近年来相关文献进行整理和分析,总结了心脑血管疾病瘀毒互结证的证候特点及活血解毒法的临床实践基础,从现代医学角度剖析了心脑血管疾病瘀毒互结证的生物学基础。提出未来研究应规范病证结合诊断标准、借助多学科优势探索证候生物学基础及建立稳定的病证结合动物模型等观点,以期为心脑血管疾病的防治提供思路和启发。 The combination of blood stasis and toxin is a common syndrome of cardiovascular and cerebrovascular diseases,and it is also the key pathogenesis of disease prolongation and deterioration.This article summarizes the characteristics of blood stasis and toxin syndrome of cardiovascular and cerebrovascular diseases and the clinical practice basis of the promoting blood circulation and detoxication method.In addition,from the perspective of modern medicine,the biological basis of the blood stasis and toxin syndrome of cardiovascular and cerebrovascular diseases are analyzed.It is proposed that future research should standardize the diagnosis criteria of the disease-syndrome,explore the biological basis of the disease with the help of multidisciplinary advantages,and establish a stable disease-syndrome animal model,so as to provide ideas and inspiration for the prevention and treatment of cardiovascular and cerebrovascular diseases.
作者 刘悦 梁晓 魏竞竞 申伟 刘红喜 迟显苏 张允岭 LIU Yue;LIANG Xiao;WEI Jing-jing;SHEN Wei;LIU Hong-xi;CHI Xian-su;ZHANG Yun-ling(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China)
出处 《中华中医药杂志》 CAS CSCD 北大核心 2023年第3期937-941,共5页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家中医药管理局中医药创新团队及人才支持计划项目(No.ZYYCXTD-C-202007) 中国中医科学院科技创新工程项目(No.CI2021A01301) 中国中医科学院中医药防治脑病传承创新团队(No.CI2021B006) 国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄学者)—国家中医药领军人才支持计划(No.国中医药人教发〔2018〕12号)。
关键词 心脑血管疾病 瘀毒互结证 生物学基础 诊断标准 动物模型 Cardiovascular and cerebrovascular diseases Blood stasis and toxin syndrome Biological basis Diagnostic criteria Animal model
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