摘要
糖尿病足溃疡在老年糖尿病人群中常见。对糖尿病足溃疡复杂的分子水平机制研究仍在不断探索中,细胞衰老对糖尿病足溃疡愈合延迟的作用受到关注,分析细胞衰老与糖尿病足溃疡的关系,探索细胞衰老延缓糖尿病足伤口愈合的作用机制,明确清除衰老细胞、延缓细胞衰老的治疗方法,可为研发糖尿病足溃疡药物提供新的治疗靶点和策略。
Diabetic foot ulcers are common in elderly people with diabetes.Ongoing research is aimed at unraveling the complicated molecular mechanisms underlying diabetic foot ulcers.The role of cellular aging in delayed healing of diabetic foot ulcers has been recognized.Analyzing the relationship between cellular aging and diabetic foot ulcers,examining how cellular aging delays the healing of diabetic foot wounds,and identifying treatment methods for the removal of senescent cells and for slowing down cellular senescence will provide new therapeutic targets and strategies for the development of drugs for diabetic foot ulcers.
作者
包易如
朱朝军
张朝晖
Bao Yiru;Zhu Zhaojun;Zhang Zhaohui(Graduate School of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;Department of Traditional Chinese Medicine,The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300250,China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2023年第3期361-365,共5页
Chinese Journal of Geriatrics
基金
国家自然科学基金面上项目(81973853)
国家重点研发计划(2019YFC1709303)。
