瘢痕疙瘩分期分阶段治疗的效果

Clinical efficacy of graded and staged treatment on keloid

目的:探讨瘢痕疙瘩的分期分阶段治疗,优化治疗方案。方法:2005年6月至2019年6月,潍坊市人民医院美容整形科收治瘢痕疙瘩患者629例,男253例、女376例,年龄9~78(31.3±16.8)岁。根据病情按分期由低到高施以3个阶段综合治疗、定期观察效果,并对复发率进行统计。结果:Ⅰ期251例患者治疗后6个月局部复发14例,占5.5%;24个月复发4例,占1.6%;经再次注射治疗后痊愈。Ⅱ期302例患者治疗后6个月局部复发56例,占18.6%;经再次治疗后49例(87.5%)患者痊愈,24个月复发35例,占11.6%。Ⅲ期76例患者治疗后6个月复发36例,占47.3%;再次治疗后24个月复发19例,占25%。结论:瘢痕疙瘩综合治疗后效果和复发率与其严重程度有关,根据病情分期分阶段治疗能获得较满意的效果。

Objective To explore the staged treatment of keloid scars and to optimise treatment options.Methods From June 2005 to June 2019,629 keloid patients,253 males and 376 females,aged 9 to 78 years,with a mean age of 31.3±16.8 years,were admitted to the Department of Aesthetic Plastic Surgery of Weifang People's Hospital.Three-stage comprehensive treatment was administered according to the stage of the disease from low to high,and the treatment effect was observed regularly,and the recurrence rate was counted.Results In stageⅠ,251 patients had local recurrence in 14 cases(5.5%)and 4 cases(1.6%)at 2 years 6 months after treatment,all of whom were cured after re-injection;in stageⅡ,302 patients had local recurrence in 56 cases(18.6%)at 6 months after treatment,49 patients(87.5%)were cured after re-treatment and 35 patients(11.6%)at 2 years;in stageⅢ,at 6 months after treatment,36 patients(47.3%)had recurrence and 19 patients(25%)had recurrence at 2 years after re-treatment.Conclusions The results and recurrence rate of keloids after comprehensive treatment are related to their severity,and a more satisfactory outcome can be achieved by staging the treatment according to the stage of the disease.