食品接触材料中2,2,4,4-四甲基-1,3-环丁二醇迁移量的测定

Determination of Migration of 2,2,4,4-tetramethyl-1,3-cyclobutanediol in Food Contact Materials

采用气质联用技术,建立了食品接触材料中2,2,4,4-四甲基-1,3-环丁二醇迁移量的分析方法。样品经4%乙酸、10%乙醇、20%乙醇、50%乙醇、橄榄油、95%乙醇、异辛烷浸泡后得到浸泡溶液,经有机溶剂提取后供气质联用仪分析,外标法定量。水基、酸性、乙醇类、橄榄油食品模拟物及化学替代溶剂中2,2,4,4-四甲基-1,3-环丁二醇的检出限在0.008~0.080 mg/L之间,方法的平均回收率在90.2%~107.8%之间,相对标准偏差在2.61%~9.04%之间。该方法前处理简单,检测速度快,灵敏度高,满足食品接触材料中2,2,4,4-四甲基-1,3-环丁二醇迁移量的分析要求。

A analytical method for determination of 2,2,4,4-tetramethyl-1,3-cyclobutanediol migration in food contact materials was established by gas chromatography-mass spectrometry(GC-MS) technology. The sample was soaked in 4%acetic acid,10% ethanol,20% ethanol,50% ethanol,olive oil,95% ethanol and isooctane to obtain the soaking solution,and then extracted by organic solvent. The detection limits of 2,2,4,4-tetramethyl-1,3-cyclobutanediol in water-based,acidic,alcoholic,olive oil food simulants and chemical alternative solvents are between 0.008 and 0.080 mg/L. The average recovery of the method is between 90.2% and 107.8%,and the relative standard deviation is between 2.61% and 9.04%. This method has the advantages of simple pretreatment,fast detection speed and high sensitivity,and can meet the requirements of analysis of migration of 2,2,4,4-tetromethyl-1,3-cyclobutanediol in food contact materials.