黄芪、板蓝根对山羊生长性能及免疫、抗氧化功能的影响

Effects of radix Astragali and radix isatidis on growth performance, immune and antioxidant functions of goats

研究旨在探讨黄芪、板蓝根对山羊生长性能及血清免疫、抗氧化功能的影响。试验选取15只平均体重为(18.44±5.75) kg、日龄为(210±30) d的本地山羊,随机分成5组,每组3只羊(一公两母)。对照组山羊饲喂基础日粮,各试验组分别在基础日粮中添加0.8%、1.6%的黄芪粉和0.8%、1.6%板蓝根粉。试验期70 d。结果显示:试验期内,黄芪添加组山羊的平均日增重均显著高于其他组(P<0.05),且黄芪高剂量组最高。试验14、28 d,黄芪高剂量组山羊血清碱性磷酸酶(ALP)的活性和生长激素(GH)的含量均显著高于其他组(P<0.05);黄芪高剂量组山羊血清丙二醛(MDA)含量显著低于其他组(P<0.05),超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性显著高于其他组(P<0.05);黄芪低剂量组山羊血清GSH-Px活性显著高于对照组和板蓝根添加组(P<0.05);黄芪高剂量组山羊血清球蛋白(GLB)、白蛋白(ALB)、免疫球蛋白A (IgA)、免疫球蛋白G (IgG)、免疫球蛋白M (IgM)、白细胞介素-2 (IL-2)及α-干扰素(IFN-α)含量均显著高于其他组(P<0.05)。研究表明,在日粮中添加1.6%黄芪粉能够促进山羊生长,提高山羊抗氧化能力、改善免疫水平。

The aim of the study was to investigate the effects of radix Astragalus and radix isatis on immune performance,antioxidant capacity and growth performance of goats. Fifteen local goats with an average body weight of(18.44±5.75) kg and age of(210±30) d were randomly divided into five groups with three goats(one male and two female) per group.Goats in control group were fed a basal diet, and experimental groups were fed the basal diet supplemented with 0.8% and 1.6% Astragalus powder and 0.8% and 1.6% isatis powder, respectively. The experiment lasted for 70 d. The results showed that during the trial period, the average daily gain of goats in Astragalus supplemental group was significantly higher than that in other groups(P<0.05), and the highest value was found in Astragalus high-dose group. On 14th and 28th d, the serum alkaline phosphatase activity and growth hormone content of Astragalus high-dose group were significantly higher than those of other groups(P<0.05). The content of MDA in serum of Astragalus high-dose group was significantly lower than that of other groups(P<0.05), and the activitiy of SOD and GSH-Px in serum of goats in Astragalus high-dose group were significantly higher than those in other groups(P<0.05). Serum GSH-Px activity of Astragalus low-dose group was significantly higher than that of control group and radix isatidis supplemental group(P<0.05). The content of ALB, GLB, Ig A, Ig G, Ig M, IL-2 and IFN-α in serum of Astragalus high-dose group were significantly higher than those of other groups(P<0.05). The study indicates that adding 1.6% Astragalus powder in goat diet can promote the growth, increase the antioxidant capacity and improve the immune level of goats.