用药科普干预在长期服用拉莫三嗪癫痫患者中的应用

Application of medication popular science intervention in the treatment of epilepsy patients with long-term use of lamotrigine

目的探讨用药科普干预在长期服用拉莫三嗪治疗的癫痫患者中的应用效果,以期为临床治疗提供参考。方法本研究选取郑州大学附属洛阳中心医院2021年3—9月收治的120例癫痫患者为研究对象。采用随机数字表法将患者分为常规组与科普干预组,每组60例。常规组患者采用拉莫三嗪常规用药治疗。科普干预组患者在常规组基础上进行药物科普干预。比较2组患者出院时Morisky用药依从性问卷(MMAS-8)评分;比较2组患者出院时癫痫知识掌握情况。结果科普组患者用药依从率高于常规组,差异有统计学意义(P<0.05)。科普干预组患者了解率高于常规组,差异有统计学意义(P<0.05)。结论用药科普干预在长期服用拉莫三嗪治疗的癫痫患者中的效果显著,可提高患者的用药依从性及相关知识了解率,增强其自我管理意识,安全有效,值得临床推广应用。

Objective To investigate the effect of medication popular science intervention in the treatment of epilepsy patients with long-term use of lamotrigine,so as to provide a reference for clinical treatment.Methods A total of 120 patients with epilepsy admitted to Luoyang central hospital affiliated to Zhengzhou university from March to September 2021 were selected as the study participants.They were assigned to a conventional group and a popular science intervention group by random number table,with 60 cases in each group.Patients in the conventional group received lamotrigine.Patients in the popular science intervention group underwent medication popular science intervention based on the conventional group.The eight-item Morisky Medication Adherence Scale(MMAS-8)scores at discharge were compared between the two groups;epilepsy knowledge at discharge was compared between the two groups.Results The compliance rate of patients in the medication popular science intervention group was significantly higher than that in the conventional group(P<0.05).The understanding rate of patients in the medication popular science intervention group was significantly higher than that in the conventional group(P<0.05).Conclusion Medication popular science intervention is effective in treating epileptic patients with longterm use of lamotrigine,which can improve medication compliance and relevant knowledge rate,and promote patients'selfmanagement awareness,with safe and effective profiles.These benefits justify a wider application of this procedure clinically.