肺动脉去神经术治疗肺动脉高压的研究进展

Research progress on pulmonary arterial denervation for pulmonary arterial hypertension

交感神经过度激活加重肺动脉高压(pulmonary arterial hypertension,PAH)的进展,肺动脉去神经术(pulmonary artery denervation,PADN)是最近提出的一种有利于治疗PAH和混合型毛细血管后和前肺动脉高压(combined pre-capillary and post-capillary pulmonary hypertension,Cpc-PH)的介入方法,相关的临床试验初步证实了PADN的有效性及安全性。本文着重介绍PADN治疗的临床证据及操作流程。

Excessive activation of sympathetic nerves aggravates the progress of pulmonary arterial hypertension(PAH).Pulmonary artery denervation(PADN)is a new interventional approach for the treatment of PAH,as well as combined pre-capillary and post-capillary pulmonary hypertension(Cpc-PH).Preliminary trials have confirmed the efficacy and safety of PADN.This article focuses on the clinical evidence and procedure steps of PADN treatment.