科学严谨的患者信息登记是高质量胃癌外科研究的基石——荷兰上消化道癌症审计数据库11年经验分享

Scientific and rigorous data registration of patients with gastric cancer is the cornerstone of high-quality surgical research on gastric cancer:lessons learned from the Dutch upper gastrointestinal cancer audit(DUCA)

随着过去数十年微创技术、围手术期康复干预和集中化医疗制度的逐步应用,胃癌术后30 d病死率和并发症发生率有了显著改善。然而,当前阶段的胃癌术后短期预后依然不容乐观,可能对胃癌手术治疗的疗效产生严重的负面影响,仍有很大的改善空间。高质量的临床研究是分析治疗结果和评估新治疗策略的重要工具。因此,严谨的胃癌患者信息登记作为高质量外科研究的基础应受到足够重视。在过去的11年里,荷兰上消化道癌症审计(DUCA)数据库在上消化道肿瘤患者的数据登记和维护方面拥有丰富的经验,它在数据登记、数据质量控制、数据申请和使用以及数据安全等方面采取的有效措施,使得该数据库中患者数据的质量保持在较高水平。这些数据已被广泛用于医疗质量监测和科学研究,对改善上消化道癌症患者的术后短期预后产生了非常积极的影响。DUCA的工作可能对建立基于人群的临床数据库具有一定的参考价值。

The postoperative 30-day mortality and morbidity of gastric cancer surgery has markedly improved over the past years due to minimally invasive techniques,perioperative rehabilitation programs and centralization of care.However,there is still need for improvement as postoperative complications may have a serious negative impact on the efficacy of surgical treatment of gastric cancer.High-quality clinical research is a very important tool to analyze treatment outcomes and evaluate new treatment strategies.The meticulous registration of gastric cancer patient data is the basis of high-quality surgical research.In the past 11 years,the Dutch upper gastrointestinal cancer audit(DUCA)database has vast experience in data registration and maintenance of patients with upper gastrointestinal cancer.The effective measures it has taken in data registration,data quality control,data application and use,and data security have maintained quality at a high level.These data has been used for medical care quality monitoring and scientific research leading to a positive impact on the postoperative short-term outcomes of patients with upper gastrointestinal cancer.The work of DUCA may be a good incentive for the setup of population-based databases and clinical research in other countries.