基于中医体质学“体病相关”理论探究痰湿体质与哮喘的相关性

The correlation between phlegm-dampness constitution and asthma based on the theory of“constitution-disease relation”of TCM constitution

“体病相关”理论是中医体质学研究的关键科学问题,该理论认为,不同的体质类型与某些特定疾病的发生密切相关。本文基于“体病相关”三说——易感说、从化说、土壤说阐述了痰湿体质与哮喘的内在联系,认为以肥胖为主要外在表型的痰湿体质其特定的生理病理学基础和遗传基因的易感性使得该体质易罹患哮喘,痰湿体质是哮喘的发病土壤。而且痰湿体质人群的个体差异影响着哮喘的病因病机、病变性质和转归预后。因此,临床上诊治肥胖相关哮喘时,通过调理痰湿体质可能会取得主观症状和客观指标的双重收益。

The theory of“constitution-disease relation”is a key scientific problem in the study of constitution in traditional Chinese medicine.The theory states that different constitution types are closely related to the occurrence of some specific diseases.Based on the three theories of constitution-disease relation:the susceptibility theory,the transformation theory,and the soil theory,we expounds the internal relationship between phlegm-dampness constitution and asthma.It is believed that the specific physiological and pathological basis and the genetic susceptibility of phlegm-dampness constitution with obesity as the main external phenotype make this constitution type susceptible to asthma.Phlegm-dampness constitution is the soil of asthma.Moreover,individual differences in the phlegm-dampness constitution population affect the etiology and pathogenesis,the nature of the lesion,and prognosis of asthma.Therefore,both subjective symptoms and objective indicators may be benefited by regulating phlegm-dampness constitution in the diagnosis and treatment of obesity-related asthma clinically.