体外物理振动排石联合盐酸坦索罗辛缓释胶囊治疗输尿管结石的疗效分析

Effect of external physical vibration lithecbole combined with tamsulosin hydrochloride sustained-release capsule on ureteral calculi

目的 探讨体外物理振动排石(EPVL)联合盐酸坦索罗辛缓释胶囊治疗结石长径<6 mm的输尿管结石的临床效果.方法 选取2018年10月至2020年12月本院收治的220例结石长径<6 mm的输尿管结石患者,并按照随机数字表法分为对照组和研究组,每组各110例.对照组采用EPVL治疗,研究组在对照组基础上加用盐酸坦索罗辛缓释胶囊治疗.比较两组的排石情况、术后并发症发生率等.结果 研究组的当日排石率、1周排石率、2周排石率均高于对照组,差异均有统计学意义(49.1%、67.3%、77.3%vs.29.1%、44.5%、51.8%,均P<0.05).研究组的肾绞痛及血尿发生率低于对照组,差异均有统计学意义(8.2%vs.21.8%,16.4%vs.28.2%,均P<0.05).结论 EPVL联合盐酸坦索罗辛缓释胶囊治疗结石长径<6 mm的输尿管结石是一种安全有效的治疗方案,能提高排石效果,促进患者康复,值得临床推广.

Objective To explored the clinical effect of external physical vibration lithecbole(EPVL)combined with tamsulosin hydrochloride sustained-release capsule in the treatment of ureteral calculi(<6 mm).Methods A total of 220 patients with ureteral calculi with the long diameter of stones<6 mm admitted to our hospital from October 2018 to December 2020 were selected and divided into a control group and a study group according to the random number table method,with 110 cases in each group.The control group was treated with EPVL,and the study group was treated with tamsulosin hydrochloride sustained release capsule on the basis of the control group.The stone expulsion rate and the incidence of complications were compared between the two groups.Results The stone removal rate of the study group was higher than that of the control group in the first day,one week and two weeks(49.1%,67.3%,77.3%vs.29.1%,44.5%,51.8%,all P<0.05).The incidence of renal colic and hematuria in the study group was lower than that in the control group,and the difference was statistically significant(8.2%vs.21.8%,16.4%vs.28.2%,all P<0.05).Conclusions EPVL combined with tamsulosin hydrochloride sustained release capsule is a safe and effective treatment for ureteral stones(stone long diameter<6 mm),which can improve the stone removal effect and promote the rehabilitation of patients,and is worthy of clinical promotion.