血液病形态学检查和整合诊断思路

Morphological examination and integrated diagnosis of hematologic diseases

以骨髓涂片为主和/或血片进行的血液病形态学检查,需要与时俱进。几种形态学方法之间需要进行优化互补,四片(骨髓涂片、血片、骨髓印片和骨髓切片)联检即是一种较为完善的整合模式,与有意义的形态学新检验项目一起,可以明显地提升形态学的可靠诊断。同时在诊断思路上也需要进行扩展与深化,整合临床、免疫表型和遗传学思路,并以诊断证据与规则为标尺,已是现代形态学检验诊断的主旋律。

The morphologic examination of hematologic diseases,mainly by bone marrow smear and/or blood smear needs to keep pace with the times.Several morphological methods need to be optimized and complemented.The joint examination of bone marrow smear,blood smear,bone marrow biopsy imprint and bone marrow section is a relatively complete integrated mode.Together with the meaningful new morphological test items,the reliable diagnosis of morphology can be significantly improved.At the same time,it is also necessary to expand and deepen the diagnostic thinking,integrate clinical,immunophenotype and genetic thinking,and take diagnostic evidence and rules as the criterion,which was the main theme of modern morphological inspection and diagnosis.