中文版特应性皮炎控制工具的信效度与反应度的验证性研究

Validation study of the Chinese version of atopic dermatitis control tool

为验证中文版特应性皮炎控制工具(atopic dermatitis control tool,ADCT)的信效度和反应度。本研究在获得中文版ADCT量表的授权后,采用便利抽样法,选取2022年10月于北京大学第一医院皮肤科就诊的114例特应性皮炎患者作为研究对象。使用一般资料调查表、中文版ADCT、患者湿疹自我测评量表(patient-oriented eczema measure,POEM)、峰值瘙痒数字评定量表(peak pruritus numerical rating scale,PP-NRS)、皮肤生活质量指数(dermatology life quality index,DLQI)和患者报告的疾病整体严重程度对患者进行调查。采用Mann-Whitney秩和检验和Spearman相关分析进行项目分析;采用内容效度指数(content validity index,CVI)评估内容效度;采用探索性因子分析评估结构效度;采用Cronbach′α系数评定内部一致性;采用Spearman相关分析评估ADCT与其他量表的相关性来评估外部反应度。结果显示,经项目分析保留所有条目。I-CVI为0.9~1,S-CVI/Average为0.983;经因子分析提取1个公因子,累计方差解释率为77.927%;量表Cronbach′α系数为0.937;中文版ADCT与POEM、PP-NRS、DLQI的相关系数分别为0.805、0.861、0.709。综上,中文版ADCT具有良好的信效度和反应度,适合测量评估中国特应性皮炎患者的疾病控制情况。

To assess the reliability,validity and responsiveness of the Chinese version of the atopic dermatitis control tool(ADCT).After this study obtained authorization for the Chinese version of the ADCT scale.114 patients with atopic dermatitis were enrolled from the Department of Dermatology,Peking University First Hospital using convenience sampling from October 2022.Patients were surveyed using the General Information Questionnaire,Chinese version of ADCT,patient-oriented eczema measure(POEM),peak pruritus numerical rating scale(PP-NRS),dermatology life quality index(DLQI)and the global patient self-assessment for disease severity.Mann-Whitney rank sum test and Spearman correlation analysis were used for item analysis;content validity was assessed using content validity index(CVI);exploratory factor analysis was used to assess structural validity;Cronbach′alpha coefficient was used to assess internal consistency;Spearman correlation analysis was used to assess the correlation of ADCT with other scales to assess external responsiveness.The results showed that all items were retained by item analysis.I-CVI was 0.9-1,and S-CVI/Average was 0.983;the scale extracted one common factor by factor analysis,the cumulative variance explanation rate was 77.927%;the Cronbach′alpha coefficient of the scale was 0.937;the correlation coefficients of the Chinese version of ADCT with POEM,PP-NRS,and DLQI were 0.805,0.861,and 0.709 respectively.In conclusion,the Chinese version of the ADCT has adequate reliability,validity and responsiveness,and is suitable for measuring disease control in Chinese patients with atopic dermatitis.