基于循证指导的中医延续护理对轻中度活动期溃疡性结肠炎患者的影响

Effect of evidence-based continuous nursing of traditional Chinese medicine on patients with mild-to-moderate ulcerative colitis

目的 评价基于循证指导的中医延续护理在轻中度活动期溃疡性结肠炎患者中的实施效果和价值。方法 选取2021年1月至2022年3月华中科技大学同济医学院附属协和医院收治的共计106例轻中度活动期溃疡性结肠炎患者作为研究对象,按简单随机抽样法进行分组。对照组(53例)给予常规护理,观察组(53例)联合基于循证指导的中医延续护理。比较2组的康复效果、神经内分泌因子水平以及生活质量。结果 观察组的治疗总有效率为96.23%,较对照组的84.91%更高(P<0.05)。出院时和出院3个月后,2组的血管活性肠肽(VIP)水平均较干预前升高,P物质(SP)水平均较干预前下降(P均<0.05);观察组的VIP水平均较同期对照组更高,SP水平均较同期对照组更低(P均<0.05)。出院时和出院3个月后,2组的炎症性肠病患者生活质量分析表4个维度评分均较干预前升高(P均<0.05),且观察组均较同期对照组更高(P均<0.05)。结论 基于循证指导的中医延续护理干预对轻中度活动期溃疡性结肠炎患者康复效果和生活质量的提升,以及神经内分泌因子水平的调节均可起到积极作用。

Objective To evaluate the implementation effect and value of evidence-based continuous nursing of traditional Chinese medicine in patients with mild-to-moderate ulcerative colitis.Methods A total of106 patients with mild-to-moderate ulcerative colitis were selected from Union Hospital,Tongji Medical College,Huazhong University of Science and Technology between January 2021 and March2022,and they were grouped through simple random sampling.The control group(53 cases)received routine nursing,and the observation group(53 cases)additionally received evidence-based continuous nursing of traditional Chinese medicine.The rehabilitation effect,neuroendocrine factor levels,and quality of life of the two groups were compared.Results The total effective rate of the observation group was96.23%,which was higher than84.91%of the control group(P<0.05).At discharge and3 months after discharge,the vasoactive intestinal peptide(VIP)level in both groups was higher than that before intervention,and the substance P(SP)level was lower than that before intervention(allP<0.05).The observation group had a higher VIP level and a lower SP level than the control group(all P<0.05).At discharge and 3 months after discharge,the scores of 4 dimensions of the Inflammatory Bowel Disease Questionnaire in both groups were higher than those before intervention(allP<0.05),and the observation group had higher scores than the control group(allP<0.05).Conclusion Evidence-based continuous nursing intervention of traditional Chinese medicine plays a positive role in improving the rehabilitation effect and quality of life of patients with mild-to-moderate ulcerative colitis and regulating their levels of neuroendocrine factors.