经尿道前列腺钬激光剜除术治疗大体积前列腺增生的临床观察

Clinical Observation on Transurethral Holmium Laser Enucleation of Prostate in the Treatment of Massive Benign Prostatic Hyperplasia

目的探讨经尿道前列腺钬激光剜除术(HoLEP)治疗大体积前列腺增生(BPH)的临床效果。方法将2017年1月至2020年2月我院收治的100例大体积BPH患者随机分为两组各50例。治疗组行HoLEP,对照组行经尿道前列腺电切术(TURP)。比较两组的手术相关指标、IPSS、PVR、Qmax、并发症。结果治疗组术中出血量少于对照组,膀胱持续冲洗时间、手术时间、住院时间、导尿管留置时间短于对照组(P<0.05)。术后,治疗组IPSS、PVR低于对照组,Qmax高于对照组(P<0.05)。治疗组术后并发症发生率为4.00%,低于对照组的20.00%(P<0.05)。结论与TURP相比,HoLEP治疗大体积BPH具有失血量少、手术时间短、并发症少、IPSS及PVR低、Qmax高、恢复快等优点,值得临床推广。

Objective To explore the clinical effect of transurethral holmium laser enucleation of prostate(HoLEP)in the treatment of massive benign prostatic hyperplasia(BPH).Methods 100 patients with massive BPH admitted to our hospital from January 2017 to February 2020 were randomly divided into two groups,with 50 cases in each group.The treatment group received HoLEP,and the control group received transurethral resection of prostate(TURP).The operation-related indicators,IPSS,PVR,Qmax and complications were compared between the two groups.Results The intraoperative blood loss of the treatment group was less of the control group,and the bladder continuous irrigation time,operation time,hospitalization time and catheter indwelling time were shorter than those of the control group(P<0.05).Afer operation,the IPSS and PVR of the treatment group were lower than those of the control group,and the Qmax was higher than that of the control group(P<0.05).The incidence of postoperative complications in the treatment group was 4.00%,lower than 20.00% in the control group(P<0.05).Conclusions Compared with TURP,HoLEP has the advantages of less blood loss,shorter operation time,fewer complications,lower IPSS and PVR,higher Qmax,and faster recovery,which is worthy of clinical promotion.