摘要
Aging causes changes in synaptic plasticity,myelination,vasculature,and cognitive function[l].Accumulating evidence highlights that improvement of the systemic environment benefits brain function and alleviates brain aging.Such improvements include heterochronic parabiosis,transplantation of bone marrow,young blood,or fecal microbiota,and plasma transfer experiments[2-5].
基金
supported by a grant from the National Institute of Aging,National Institutes of Health(1RF1AG058603).