2002—2020年上海市杨浦区居民糖尿病相关疾病死亡变化趋势及早死概率分析

Changing trend in diabetes-related death and probability of premature mortality among residents in Yangpu District of Shanghai from 2002 to 2020

【目的】分析上海市杨浦区居民糖尿病相关疾病死亡变化趋势及早死概率,为制定相关干预策略提供依据。【方法】收集2002—2020年上海市杨浦区居民死因监测数据和人口数据资料,采用SPSS 21.0软件和Excel 2010软件进行统计分析,采用χ^(2)检验进行死亡率的比较,采用Joinpoint线性回归分析年度变化百分比(APC),率的标化采用2000年世界标准人口。【结果】2002—2020年上海市杨浦区累计报告糖尿病相关疾病死亡25091例,年均粗死亡率为122.10/10万,男性粗死亡率116.13/10万,女性粗死亡率128.23/10万,男性与女性差异有统计学意义(P<0.05)。糖尿病相关疾病死亡病例的根本死因依次为糖尿病、心脑血管疾病和肿瘤。在糖尿病死亡病例中,伴有周围循环并发症的最多,占50.79%,其次是肾并发症,占16.05%。糖尿病相关疾病粗死亡率(男性、女性、合计)均呈上升趋势,标化死亡率整体保持平稳,男性呈上升趋势,女性呈下降趋势;糖尿病合并心脑血管疾病粗死亡率(男性、女性、合计)均呈上升趋势;合计和男性的标化死亡率均呈上升趋势,女性则保持平稳;糖尿病粗死亡率整体呈上升趋势,男性呈上升趋势,女性整体保持平稳,糖尿病标化死亡率整体呈下降趋势,男性呈上升趋势,女性呈下降趋势。2002—2020年糖尿病相关疾病、糖尿病合并心脑血管疾病和糖尿病所导致的早死概率总体趋势无统计学意义,但男性均呈上升趋势,女性均呈下降趋势。【结论】上海市杨浦区糖尿病相关疾病、糖尿病合并心脑血管疾病、糖尿病的粗死亡率均呈上升趋势,3种疾病的男性标化死亡率和早死概率也均呈上升趋势,提示要重点关注男性糖尿病患者的健康,采取有针对性的措施,降低疾病负担。

[Objective]To determine the trend in diabetes-related death and probability of premature mortality among residents in Yangpu District of Shanghai and provide evidence for the formulation of relevant intervention strategies.[Methods]Mortality and demographic data were collected among residents in Yangpu District of Shanghai from 2002 to 2020.Statistical analysis was conducted using chi-square test with SPSS 21.0 and Excel 2010.Joinpoint regression was used to determine annual percent change(APC).The mortality was standardized by utilizing the world standard population in 2000.[Results]A total of 25091 cases of diabetes-related deaths were reported in Yangpu District,Shanghai from 2002 to 2020.The average annual crude mortality of diabetes-related diseases was 122.10/105,which was 116.13/105 in males and 128.23/105 in females.The difference between males and females in crude mortality was statistically significant(P<0.05).Moreover,primary causes of diabetes-related deaths were diabetes,cardiovascular and cerebrovascular diseases,and tumors.Among diabetic deaths,peripheral circulatory complications accounted for 50.79%,followed by renal complications(16.05%).The crude mortality in males,females,and total of diabetes-related diseases showed an upward trend,while the standardized mortality remained stable with an upward trend in male and a downward trend in female.Furthermore,the crude mortality in males,females,and total of diabetes complicated with cardiovascular and cerebrovascular diseases showed an increasing trend.In contrast,both the standardized mortality in males and in total showed an increasing trend,while that in females remained stable.The overall crude mortality of diabetes was on the rise,which was increasing in males and stable in females.The overall standard mortality of diabetes was on the decline,which was increasing in males while declining in females.In addition,the probability of premature mortality caused by diabetes-related diseases,cardiovascular and cerebrovascular diseases complicated with diabetes,and diabetes decreased from 2002 to 2020 with no statistical significance.Males showed an upward trend while females showed a downward trend.[Conclusion]The mortality of diabetes-related diseases,cardiovascular and cerebrovascular diseases complicated with diabetes,and diabetes among residents in Yangpu District of Shanghai is on the rise.Similarly,standardized mortality and probability of premature mortality in males for all three diseases are also on the rise.It warrants more attention to the health of male diabetes patients and targeted measures to reduce the disease burden.