音乐疗法对失眠障碍患者应用效果的Meta分析

Clinical effect of music therapy in patients with insomnia:a meta-analysis

目的系统评价音乐疗法对失眠障碍患者的疗效。方法使用计算机对PubMed、Web of Science、Embase、中国生物医学文献数据库、中国知网、万方数据库、维普数据库进行检索。检索时间为建库截止到2021年12月3日;并严格按照纳入排除标准进行文献的筛选及数据提取;通过RevMan 5.3和Stata 16.0软件进行数据的分析与评价。结果共纳入20篇RCT文章,纳入总人数为1378例(试验组:704例;对照组:703例)。Meta分析结果显示通过音乐疗法可有效改善患者的失眠症状,其中临床有效率(RR=1.66,95%CI 1.35~2.05,P<0.001)、PSQI评分(WMD=-1.10,95%CI-1.57~-0.63,P<0.001)、ISI评分(WMD=-0.30,95%CI-0.76~-0.15,P=0.19)结果分析均具有统计学差异。结论音乐疗法在治疗失眠障碍患者的临床观察具有明显的优势与治疗意义。结局指标的选择方面大多文献均采用临床有效率和PSQI评分两种,因此,在结局观察可扩充多方面的睡眠观察指标。

Objective To systematically review the clinical effect of music therapy in patients with insomnia.Methods PubMed,Web of Science,Embase,CBM,CNKI,Wanfang Data,and VIP were searched for related articles published up to December 32021,and literature screening and data extraction were performed strictly according to the inclusion and exclusion criteria.RevMan 5.3 and Stata 16.0 were used for data analysis and evaluation.Results A total of 20 randomized controlled trial articles were included,with 1378 patients in total,among whom there were 704 patients in the experimental group and 703 patients in the control group.The meta-analysis showed that music therapy effectively improved the symptoms of patients with insomnia,with significant differences in clinical response rate(risk ratio=1.66,95%confidence interval[CI]:1.35-2.05,P<0.001),PSQI score(weighted mean difference[WMD]=-1.10,95%CI-1.57 to-0.63,P<0.001),and ISI score(WMD=-0.30,95%CI-0.76 to-0.15,P=0.19).Conclusion Music therapy has obvious advantages and therapeutic significance in the clinical observation of patients with insomnia.Clinical response rate and PSQI score are mainly selected as outcome measures in most articles,and therefore,more sleep indicators can be used for outcome observation.