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某儿童医院围手术期止血药物预防性用药情况分析 被引量:1

Analysis on the Prophylactic Use of Hemostatic Drugs During Perioperative Period in a Children's Hospital
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摘要 目的:调查分析某儿童医院围手术期止血药物预防性应用情况,以期促进外科围手术期止血药物的合理使用。方法:采用回顾性分析方法,通过电子信息系统调取该院2021年7~12月的外科手术病历,从中随机抽取100例围手术期预防性使用止血药物的患者,评价围手术期止血药物预防性用药的合理性。结果:共调取患者9663例,其中2687例围手术期预防性使用止血药,预防用药率为27.81%;11种止血药物均为静脉制剂,使用率排名前3位的药物依次是矛头蝮蛇血凝酶(77.30%)、酚磺乙胺(73.69%)和氨甲苯酸(72.46%)。评价100份围手术期预防性使用止血药物的电子病历,发现有不合理使用止血药物84份,存在不合理应用问题212例次,主要体现在给药时机不适宜、联合用药不适宜、用法用量不适宜和用药疗程偏长。结论:该院围手术期止血药物预防性应用存在诸多问题,需要加强对围手术期止血药物应用的督导和管理,促进临床合理用药。 Objective:To investigate and analyze the prophylactic use of hemostatic drugs during perioperative period in children's hospital,in order to promote the rational use of hemostatic drugs during perioperative period.Methods:Retrospective analysis was used to collect the surgical medical records in the hospital from July to December 2021 through electronic information system,and 100 medical records of perioperative hemostatic drugs in prophylactic use were randomly selected to evaluate the rationality of prophylactic use of perioperative hemostatic drugs.Results:A total of 9663 medical records were collected,among which 2687 cases of prophylactic use of perioperative hemostatic drugs,the rate of prophylactic use was 27.81%.All the 11 hemostatic drugs were intravenous preparations,and the top three drugs in order of use rate were hemocoagulase bothrops atrox(77.30%),etamsylate(73.69%) and aminomethylbenzoic acid(72.46%).Improper use of hemostatic drugs was found in 84 of the 100 electronic medical records extracted,and there were 212 cases of irrational use,which was mainly reflected in inappropriate timing of drug administration,inappropriate combination of drugs,inappropriate usage and dosage,and long duration of drug treatment.Conclusion:There are many problems in the prophylactic use of perioperative hemostatic drugs in the hospital.It is necessary to strengthen the supervision and management of perioperative hemostatic drugs to promote rational clinical use.
作者 刘晓玲 邢亚兵 裴保方 段彦彦 吴光华 张胜男 LIU Xiao-ling;XING Ya-bin;PEI Bao-fang;DUAN Yan-yan;WU Guang-hua;ZHANG Sheng-nan(Department of Pharmacy,Children's Hospital Affiliated to Zhengzhou University,Zhengzhou 450018,China)
出处 《中国合理用药探索》 2023年第3期73-77,共5页 Chinese Journal of Rational Drug Use
基金 河南省科技攻关项目(222102310574)。
关键词 围手术期 止血药 预防 儿童 合理用药 perioperative period hemostatic drugs prophylaxis children rational administration of drug
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