320排CT心脏四维容积动态成像评价先天性心脏病患者左心室功能研究

The value of 320-slice 4D-CCTA in evaluating left ventricular function of patients with congenital heart disease

目的:探讨320排CT心脏四维容积动态成像(4D-CCTA)评价先天性心脏病(CHD)患者左心室功能的价值。方法:选取医院收治的12例CHD患者,所有患者均行4D-CCTA检查及二维超声心动图检查,记录并对比患者左心室舒张末期容积(EDV)、收缩末期容积(ESV)、每搏输出量(SV)以及射血分数(EF)等指标;分析两种检查方法所测定结果的相关性以及4D-CCTA检查在先天性心脏病左心室功能检查中的价值。结果:4D-CCTA检查测定的EDV、SV及EF高于二维超声心动图测量值,ESV低于二维超声心动图测量值,但差异均无统计学意义。Pearson线性相关分析显示,4D-CCTA与二维超声心动图两种检查方式测定的EDV、ESV、SV及EF均具有较好的相关性(r=0.962,r=0.928,r=0.925,r=0.909;P<0.05)。4D-CCTA与二维超声心动图检查的受试者工作特征(ROC)曲线下面积(AUC)分别为0.892及0.875。结论:4D-CCTA与二维超声心动图在评价CHD患者左心室功能方面具有较高的相关性,能够准确评估CHD患者的左心室功能。

Objective:To explore the value of four-dimensional dynamic volume cardiac angiography with 320-detector computed tomography(4D-CCTA)in evaluating left ventricular function in patients with congenital heart disease(CHD).Methods:12 patients with CHD who underwent 320-slice 4D-CCTA and two-dimensional echocardiography in hospital were selected.The indexes that reflect left ventricular function included end-diastolic volume(EDV),endsystolic volume(ESV),stroke output(SV)and ejection fraction(EF)were recorded and compared.The correlation of the measured results between the two methods was analyzed,and the value of 320-slice 4D-CCTA in the examination of left ventricular function of patients with congenital heart disease was further analyzed.Results:The measured EDV,SV and EF of 4D-CCTA were higher than those of two-dimensional echocardiography,while ESV of that was lower than those of two-dimensional echocardiography,but the differences of those between the two methods was not statistically significant(P>0.05).The results of Pearson linear correlation analysis showed that there were good correlations between 4D-CCTA and two-dimensional echocardiography in detecting EDV,ESV,SV and EF(r=0.962,r=0.928,r=0.925,r=0.909,P<0.05).The area under curves(AUC)of receiver operating characteristics(ROC)curve of 4D-CCTA and two-dimensional echocardiography respectively were 0.892 and 0.875.Conclusion:4D-CCTA and two-dimensional echocardiography have higher correlation in evaluating the left ventricular function of CHD patients,which can accurately assess the left ventricular function of CHD patients.