复方嗜酸乳杆菌联合补锌治疗应用于小儿腹泻的价值评价

Value Evaluation of Compound Lactobacillus Acidophilus Combined withZinc Supplementation in Treatment of Infantile Diarrhea

目的 探讨在小儿腹泻治疗过程中复方嗜酸乳杆菌联合补锌的临床治疗效果。方法 选取2019年3月-2021年3月入院就诊的小儿腹泻患者100例作为研究对象,临床设置研究组50例,对照组50例,对照组患者采用复方嗜酸乳杆菌治疗方式,研究组患者在此治疗基础上联合使用补锌治疗方式,组间对比两组患者的营养效果以及临床时间指标。结果 治疗前,组间对比研究组患者与对照组患者,营养状况、免疫功能以及症状评分差异不显著,显示组间差异无统计学意义(P>0.05);治疗后,研究组患者组间清蛋白为(36.67±5.20)g/L,血红蛋白(96.20±4.20)g/L,IgG(9.11±2.21)g/L、IgA(1.98±0.81)g/L、症状评分(0.52±0.02)分,对照组清蛋白为(32.44±4.55)g/L,血红蛋白(92.02±4.33)g/L,IgG(8.20±2.20)g/L、IgA(1.68±0.31)g/L、症状评分(1.24±0.04)分,差异显著(P<0.05)。治疗后,组间对比两组患者临床时间指标,研究组显示排便频率恢复正常时间(2.02±0.20)d、水样便消失时间(2.02±0.11)d、发热消失时间(1.20±0.12)d、住院时间(6.34±1.02)d,对照组显示排便频率恢复正常时间(5.71±1.12)d、水样便消失时间(4.40±1.15)d、发热消失时间(1.97±0.31)d、住院时间(3.34±1.02)d,差异显著(P<0.05)。治疗后,研究组患者治疗效果明显高于对照组,差异显著(P<0.05)。结论 在小儿腹泻患者治疗中,使用复方嗜酸乳杆菌联合补锌方式,对患者预后效果进行改善,治疗时间有所缩短,营养情况改善后,免疫功能得到优化,值得临床推广。

Objective To explore clinical curative effect of compound lactobacillus acidophilus combined with zinc supplementation in treatment of infantile diarrhea.Methods The paper chose 100 cases diarrhea children admitted to hospital from March 2019 to March 2021 as study subjects,50 cases in study group and 50 cases in control group.Control group was treated with compound lactobacillus acidophilus,study group with zinc supplement on the basis of the treatment.Nutritional effect and clinical time indicators between two groups were compared between two groups.Results Before treatment,there was no significant difference in nutritional status,immune function and symptom scores between study group and control group,with no significant difference between two groups(P>0.05).After treatment,comparison between two groups showed,albumin was(36.67±5.20)g/L,hemoglobin was(96.20±4.20)g/L,IgG was(9.11±2.21)g/L,IgA was(1.98±0.81)g/L,and symptom scores were(0.52±0.02)points,while albumin in control group was(32.44±4.55)g/L,hemoglobin was(92.02±4.33)g/L,IgG was(8.20±2.20)g/L,IgA was(1.68±0.31)g/L,and symptom scores were(1.24±0.04)points,with significant difference(P<0.05).After treatment,clinical time indexes between two groups were compared.Study group showed that defecation frequency returned to normal was(2.02±0.20)d,water stool disappeared time was(2.02±0.11)d,fever disappeared time was(1.20±0.12)d,and length of stay was(6.34±1.02)d,while study showed that defecation frequency returned to normal time in control group was(5.71±1.12)d,water stool disappeared time was(4.40±1.15)d,fever disappeared time was(1.97±0.31)d,length of stay was(3.34±1.02)days,with significant difference(P<0.05).After treatment,treatment effect of study group was significantly higher than control group(P<0.05).Conclusion In treatment of children with diarrhea,compound lactobacillus acidophilus combined with zinc supplementation can improve prognosis of patients,shorten treatment time,and optimize immune function after nutritionimprovement,which is worthy of clinical promotion.