睡眠时长和睡眠质量与冠心病患病的关联性

Study on the Associations of Sleep Duration and Sleep Quality with the Prevalence of Coronary Heart Disease

目的探讨睡眠时长和睡眠质量及其在不同特征人群中与冠心病患病之间的关联。方法采用病例对照的研究方法,选取2019年7月—2020年12月福建医科大学附属第一医院和附属协和医院收治的481例冠心病患者和753例非心血管疾病患者进行问卷调查与体格检查。采用多因素logistic回归分析睡眠时长、睡眠质量与冠心病患病的关联性。结果睡眠时长<7 h/d(OR:1.678,95%CI:1.204~2.340)和睡眠质量差(OR:1.588,95%CI:1.113~2.264)是冠心病患病的独立危险因素;睡眠时长>8 h/d(OR:0.555,95%CI:0.341~0.901)是冠心病患病的保护因素。分层分析显示,≥65岁人群睡眠时长<7 h/d与冠心病患病风险增加有关,而睡眠时长>8 h/d对冠心病患病的保护作用在年龄<65岁的人群中较显著。结论睡眠时长和睡眠质量与冠心病患病风险存在关联。

Objective To explore the association of sleep duration and sleep quality with the prevalence of coronary heart disease(CHD)in a population with different characteristics.Methods Using a case-control study,481 patients with CHD and 753 non-cardiovascular patients from the First Affiliated Hospital of Fujian Medical University and the Union Hospital of Fujian Medical University from July 2019 to December 2020 were selected for questionnaire survey and physical examination.Multi-factor logistic regression was used to analyze the association between sleep duration,sleep quality and the prevalence of CHD.Results Sleep duration less than 7 h/d(OR:1.678,95%CI:1.204-2.340)and poor sleep quality(OR:1.588,95%CI:1.113-2.264)were independent risk factors for CHD,and sleep duration more than 8 h/d(OR:0.555,95%CI:0.341-0.901)was a protective factor for CHD.Stratified analysis showed that sleep duration less than 7 h/d was associated with an increased the risk of CHD in people over 65 years old,while the protective effect of sleep duration more than 8 h/d on CHD was more significant in people younger than 65 years old.Conclusion The prevalence of CHD are associated with sleep duration and sleep quality.