BIPAP治疗慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征的临床效果

Clinical effect of BIPAP on chronic obstructive pulmonary disease with obstructive sleep apnea hypopnea syndrome

目的探讨BIPAP治疗慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征的临床效果。方法选取慢性阻塞性肺疾病并发阻塞性睡眠呼吸暂停低通气综合征患者,按照数字对照法随机均等分为对照组、观察组。两组患者入院后接受COPD常规治疗措施,对照组包括吸入支气管扩张剂,平喘等呼吸道对症治疗,在以上基础上,观察组进行B1PAP无创正压通气治疗。结果治疗后,观察组的PH显著高于对照组(P<0.05),观察组的FEV1/FVC显著高于对照组(P<0.05);观察组的总有效率显著高于对照组(P<0.05)。观察组的并发症率显著低于对照组(P<0.05).治疗后,观察组的睡眠质量比对照组的睡眠质量更佳(P<0.05)。结论BIPAP无创正压通气应用于慢性阻塞性肺疾病并发阻塞性睡眠呼吸暂停低通气综合征,能够提高临床治疗总有效率,改善呼吸指标,提高睡眠质量,降低并发症率,应用于临床有很高价值。

Objective To investigate the clinical effect of BIPAP in treating chronic obstructive pulmonary disease combined with obstructive sleep apnea hypoventilation syndrome.Methods Patients with chronic obstructive pulmonary disease and obstructive sleep apnea were selected and randomly divided into control and observation groups according to the digital control method.Both groups received routine treatment for COPD after admission,and the control group included symptomatic respiratory treatment,such as inhalation of bronchodilator and flat asthma.On the above basis,the observation group performed BIPAP non-invasive positive pressure ventilation treatment.Results After treatment,the PH of the observation group was significantly higher than that of the control group(P<0.05),the FEV1/FVC of the observation group was significantly higher than that of the control group(P<0.05),and the total effective rate of the observation group was significantly higher than that of the control group(P<0.05).The complication rate in the observation group was significantly lower than that in the control group(P<0.05).After treatment,the observation group had better sleep quality than the control group(P<0.05).Conclusion The application of BIPAP non-invasive positive pressure ventilation to chronic obstructive pulmonary disease and obstructive sleep apnea hypoventilation syndrome can improve the overall efficiency of clinical treatment,improve respiratory indicators,improve sleep quality,reduce the complication rate,and have high value in clinical application.