多巴胺和去甲肾上腺素对于重症感染性休克病人PCT、CRP、Ccr、BUN等指标的调节

Effects of dopamine and norepinephrine on PCT,CRP,CCR and BUN in patients with severe septic shock

目的分析重症感染性休克病患选择多巴胺、去甲肾上腺素治疗的价值。方法将2020年12月-2022年1月纳为本次研究区间,于该区间摘选31例重症感染性休克的病患,按照治疗方式分为常规组(n=16,多巴胺治疗)、观察组(n=15,去甲肾上腺素治疗)。两组患者均接受休克纠正治疗,对比两组患者的应用效果。结果观察组患者PCT、CRP水平低于常规组患者(P<0.05);观察组患者每小时尿量、CCr、BUN均高于常规组患者(P<0.05);观察组患者动脉血乳酸水平低于常规组患者、乳酸清除率高于常规组患者(P<0.05)。结论与多巴胺相比,去甲肾上腺素有着更加显著的治疗效果,可以考虑积极推广。

Objective To analyze the value of dopamine and norepinephrine in the treatment of severe septic shock.Methods the period from December 2020 to January 2022 was included as the study interval.31 patients with severe septic shock were selected from this interval and divided into routine group(n=16,dopamine treatment)and observation group(n=15,norepinephrine treatment)according to the treatment method.Both groups of patients received shock correction treatment,and the application effects of the two groups of patients were compared.Results the levels of PCT and CRP in the observation group were lower than those in the routine group(P<0.05);The hourly urine volume,CCR and BUN in the observation group were higher than those in the routine group(P<0.05);The level of arterial blood lactic acid in the observation group was lower than that in the routine group,and the clearance rate of lactic acid was higher than that in the routine group(P<0.05).Conclusion compared with dopamine,norepinephrine has a more significant therapeutic effect,which can be actively promoted.