乳腺癌患者应用保留胸前神经和肋间臂神经的乳腺癌根治术进行治疗的临床疗效

Clinical Effect of Radical Mastectomy in Breast Cancer Patients with Thoracic Nerve and Intercostobrachial Nerve Preserved

目的 探讨对乳腺癌患者采用乳腺癌根治术(保留胸前神经以及肋间臂神经)进行治疗后获得的临床疗效。方法 选取2018年1月—2020年12月齐齐哈尔医学院附属医院收治的68例乳腺癌患者进行治疗研究。随机分为参照组(给予常规乳腺癌根治术治疗,不保留胸前神经以及肋间臂神经)和观察组[给予乳腺癌根治术(保留胸前神经以及肋间臂神经)治疗],各34例。比较两组患者各项手术指标结果、不良反应发生率、肿瘤转移率以及疾病复发率。结果 观察组术中失血量、术后引流量低于参照组,淋巴结清扫数目多于参照组、术后引流时间短于参照组,差异有统计学意义(P<0.05);观察组不良反应发生率(5.88%)低于参照组(44.12%),差异有统计学意义(χ^(2)=13.255,P<0.05);观察组肿瘤转移率以及疾病复发率均低于参照组,差异有统计学意义(P<0.05)。结论 乳腺癌根治术(保留胸前神经以及肋间臂神经)有效应用后,可改善患者各项手术指标结果,降低并发症发生率、肿瘤转移率以及疾病复发率,证明治疗安全性较高,提升患者总体预后水平。

Objective To investigate the clinical effect of radical mastectomy(sparing the thoracic nerve and the intercostobrachial nerve)in patients with breast cancer.Methods Sixty-eight patients with breast cancer admitted to the Affiliated Hospital of Qiqihar Mdeical College from January 2018 to December 2020 were selected for treatment study.They were randomly divided into thereference group,which received conventional radical mastectomy without sparing the thoracic nerve and the intercostobrachial nerve,and the observation group,which received radical mastectomy with sparing the thoracic nerve and the intercostobrachia nerve,34 cases in each group.The results of various surgical indexes,incidence of adverse reactions,tumor metastasis rate and disease recurrence rate were compared between the two groups.Results The intraoperative blood loss and postoperative drainage volume of the observation group were lower than those of thereference group,the number of lymph nodes dissection was more than that of the reference group,and the postoperative drainage time was shorter than that of thereference group,and the difference was statistically significant(P<0.05);the incidence of adverse reactions in observation group(5.88%)was lower than that in inreference group(44.12%),and the difference was statistically significant(χ^(2)=13.255,P<0.05);the tumor metastasis rate and disease recurrence rate in the observation group were lower than those in thereference group,and the difference was statistically significant(P<0.05).Conclusion Radical mastectomy(sparing the thoracic nerve and the intercostobrachia nerve)can improve the outcome of various surgical indicators.It can reduce complication rate,tumor metastasis rate and disease recurrence rate,prove high safety of treatment,improve the overall prognosis of patients.