弹性超声在早期小乳癌腋窝淋巴结转移中的预测价值

Predictive value of ultrasound elastography in axillary lymph node metastasis in early small breast cancer

目的 探讨常规超声联合弹性超声在早期小乳癌腋窝淋巴结转移中的预测价值。方法 选取女性乳腺癌患者150例,根据术后组织病理结果将患者分为腋窝淋巴结转移组44例和腋窝淋巴结非转移组106例。对乳腺肿块及腋窝淋巴结行常规超声检查,并对肿块行弹性超声检查。分析肿块、腋窝淋巴结超声图像及肿块弹性特征与腋窝淋巴结转移的相关性。结果 单因素分析显示,乳腺肿块弹性评分、组织病理学分级、腋窝淋巴结短径、皮质厚度、血供类型以及淋巴门消失情况与淋巴结转移具有相关性(P<0.05)。多因素Logistic回归分析显示,肿块弹性评分(P=0.007)、淋巴结皮质厚度(P<0.001)是早期小乳癌腋窝淋巴结转移的独立影响因素。结论 常规超声结合弹性超声对早期小乳癌腋窝淋巴结转移具有重要预测价值,有利于早诊、早治,改善患者预后。

Objective To investigate the predictive value of conventional ultrasound combined with ultrasound elastography in axillary lymph node metastasis of early small breast cancer.Methods A total of 150 female breast cancer patients were selected.According to the histopathological results,the patients were divided into axillary lymph node metastasis group(44 cases)and axillary lymph node non-metastatic group(106 cases).Conventional ultrasound was performed on the breast mass and axillary lymph nodes,and ultrasound elastography was performed on the mass.The correlations between the axillary lymph node metastasis and the ultrasound image of the mass and the elastic features of the mass were analyzed.Results Univariate analysis showed that breast mass elasticity score,histopathological grade,axillary lymph node minor diameter,cortical thickness,blood supply type and disappearance of lymphatic hilum were correlated with lymph node metastasis(P<0.05).Multivariate Logistic regression analysis showed that mass elasticity score(P=0.007)and cortical lymph node thickness(P<0.001)were independent influencing factors for axillary lymph node metastasis in early small breast cancer.Conclusion Conventional ultrasound combined with ultrasound elastography is of great value in predicting axillary lymph node metastasis of early small breast cancer,which is conducive to early diagnosis,early treatment and improvement the prognosis of patients.