应用绿色通道救治急性沼气中毒29例分析

Analysis of 29 cases of acute biogas poisoning treated with green passage

目的研究绿色通道应用于急性沼气中毒患者救治中的效果。方法纳入研究对象共29例,均为天津市第四中心医院从2017年1月-2021年12月收治的急性沼气中毒患者。采用绿色通道流程完成所有患者的救治工作。分析29例急性沼气中毒患者抢救结果,并发症发生情况,救治前后血清炎症因子水平变化情况。结果29例急性沼气中毒患者经抢救后治愈出院28例,仅有1例重度患者死亡,死亡率为3.45%。且不同严重程度急性沼气中毒患者死亡率对比均不明显(均P>0.05)。救治后29例急性沼气中毒患者意识障碍、呼吸衰竭以及肺部感染发生率均为0.00%(0/29),相较于救治前的62.07%(18/29)、13.79%(4/29)、17.24%(5/29)更低(均P<0.05)。29例急性沼气中毒患者救治后血清白细胞介素-6(IL-6)、白细胞介素-17(IL-17)水平与救治前相比更低,而白细胞介素-4(IL-4)水平为(46.57±2.39)pg/ml,比救治前的(32.44±1.48)pg/ml更高(均P<0.05)。结论绿色通道应用于急性沼气中毒患者救治中的效果显著,且有效降低并发症发生率,改善血清炎症细胞因子水平,值得推广。

Objective To study the effect of green channel in the treatment of patients with acute biogas poisoning.Methods A total of 29 patients with acute biogas poisoning admitted to the hospital from January 2017 to December 2021.Green channel flow was used to complete the rescue of all patients.To analyze the rescue results of 29 patients with acute biogas poisoning,the occurrence of complications and the changes of serum inflammatory factors before and after treatment.Results 28 of 29 patients with acute methane poisoning were cured and discharged.Only one severe patient died,the mortality was 3.45%.There was no significant difference in the mortality of the patients with different severity of acute biogas poisoning(P>0.05).After treatment,the incidence of consciousness disturbance,respiratory failure and pulmonary infection in 29 patients with acute biogas poisoning was 0.00%(0/29),it was lower than that before treatment in 62.07%(18/29),13.79%(4/29),17.24%(5/29)(all P<0.05).The levels of serum Interleukin-6(IL-6)and Interleukin-17(IL-17)in 29 patients with acute biogas poisoning after treatment were lower than those before treatment,while the levels of Interleukin-4(IL-4)were(46.57±2.39)pg/ml,it was higher than(32.44±1.48)pg/ml before treatment(all P<0.05).Conclusion The application of green channel in the treatment of patients with acute biogas poisoning has a significant effect,and effectively reduce the incidence of complications,improve the level of serum inflammatory cytokines,it is worth popularizing.