肺炎患儿发生继发性腹泻的相关危险因素分析

Risk factors of secondary diarrhea in children with pneumonia

目的探讨肺炎患儿发生继发性腹泻的危险因素。方法选取2021年1月-2022年1月上海市东方医院吉安医院收治的80例肺炎患儿,统计所有患儿继发性腹泻发生情况,根据结果分为发生组与未发生组,设计基线资料调查表,详细统计两组患者的基线资料并比较,重点分析肺炎患儿发生继发性腹泻的危险因素。结果经统计,80例肺炎患儿中发生继发性腹泻21例,占比26.25%;发生组与未发生组患儿的年龄、抗生素使用时间、联合使用抗生素、使用糖皮质激素及抗精神药物使用史比较,有统计学差异(P<0.05),组间其他资料比较,无统计学差异(P>0.05);回归分析结果显示,抗生素使用时间长、联合应用抗生素、使用糖皮质激素、有抗精神药物使用史均是肺炎患儿发生继发性腹泻的危险因素(OR>1,P<0.05),年龄大是肺炎患儿发生继发性腹泻的保护因素(OR<1,P<0.05)。结论肺炎患儿有较高的继发性腹泻发生风险,抗生素使用时间长、联合应用抗生素、使用糖皮质激素、有抗精神药物使用史均是肺炎患儿继发性腹泻发生的危险因素,年龄大是肺炎患儿发生继发性腹泻的保护因素。

Objective To explore the risk factors of secondary diarrhea in children with pneumonia.Methods 80 children with pneumonia admitted to the hospital from January 2021 to January 2022 were selected,and the incidence of secondary diarrhea in all children was counted.According to the results,all children were divided into the occurrence group and the non occurrence group.A baseline data questionnaire was designed,and the baseline data of the two groups of patients were analyzed in detail and compared,with emphasis on the risk factors of secondary diarrhea in children with pneumonia.Results According to statistics,there were 21 cases of secondary diarrhea in 80 children with pneumonia,accounting for 26.25%;there were significant differences between the occurrence group and the non occurrence group in terms of age,duration of antibiotic use,history of combined use of antibiotics,use of glucocorticoids and use of antipsychotics(P<0.05);the results of regression analysis showed that long use of antibiotics,combined use of antibiotics,use of glucocorticoids,and use of antipsychotics were all risk factors for secondary diarrhea in children with pneumonia(OR>1,P<0.05),and older age was the protective factor for secondary diarrhea in children with pneumonia(OR<1,P<0.05).Conclusion Children with pneumonia have a high risk of secondary diarrhea.Long use of antibiotics,combined use of antibiotics,use of glucocorticoids,and a history of antipsychotic use are all risk factors for secondary diarrhea in children with pneumonia.Age is a protective factor for secondary diarrhea in children with pneumonia.