反应性星形胶质细胞在慢性疼痛形成中作用的研究进展

Research progress on the mechanism of reactive astrocytes in chronic pain

慢性疼痛作为临床上常见的疾病,其发病机制尚未完全阐明。多项研究表明,在慢性疼痛发生、发展中反应性星形胶质细胞起着重要作用并且有望成为疼痛治疗的新靶标。文章对反应性星形胶质细胞在慢性疼痛形成中的作用机制及治疗前景进行总结,以期为疼痛的研究和治疗提供新思路。

Chronic pain is a common disease,but its pathological mechanisms have not been completely understood.Several studies indicated that reactive astrocytes play an important role in the occurrence and progression of pain,and have the prospect to become a novel target of pain therapy.This article reviews the mechanisms of reactive astrocytes in chronic pain and the treatment landscape,in order to provide new thoughts for the research and treatment of pain.