基于“肺与大肠相表里”理论探讨肠道菌群对肺癌影响

Exploring the influence of intestinal flora on lung cancer based on the theory of “the interior-exterior relationship between the lung and large intestine”

肺癌是当前世界性的重大疾病之一,肠道菌群是当前研究的热点,肠道菌群失调与肺癌之间存在相关性,但具体机制尚不明确。基于“肺与大肠相表里”理论,分别从“肺与大肠相表里”的理论渊源、生理基础、病理传变及治法方药等方面进行梳理,并从西医学角度阐述肠道菌群可通过炎症、免疫等途径影响肺癌的发生发展,同时影响肺癌化疗、免疫治疗等治疗效果。基于“肺与大肠相表里”经典理论探讨肠道菌群对肺癌的影响,可为肺癌的治疗提供新思路。

Lung cancer is one of the major diseases in the world, and intestinal flora is currently a hot topic of research. There is a correlation between intestinal flora dysbiosis and lung cancer, but the underlying mechanism is still unclear. Based on the theory of “the interior-exterior relationship between the lung and large intestine”, this study explores the theoretical foundation, physiological basis, pathological transmission and treatment prescriptions of lung cancer. From the perspective of modern medicine, it is further proposed that intestinal flora can influence the development of lung cancer through inflammation and immunity, and affect the therapeutic effects of chemotherapy and immunotherapy for lung cancer, with the aim to provide new ideas for the treatment of lung cancer.