高碘酸根分子钙钛矿作为新型含能杀菌剂

Periodate-based molecular perovskites as promising energetic biocidal agents

近年来,病原体引起的流行病频发,对含能杀菌剂提出了迫切需求;它们可通过爆炸性反应快速地大面积抛洒以单质碘为主的高效广谱杀菌物质,但其高碘含量与高爆性能难以同时兼得.在此,我们报道了一类新型含能杀菌剂——多碘分子钙钛矿:(H_(2)dabco)M(IO_(4))_(3)(dabco=1,4-二氮杂双环[2.2.2]辛烷,M=Na^(+)/K^(+)/Rb^(+)/NH_(4)^(+)分别对应DAI-1/2/3/4)和(H_(2)dabco)Na(H_(4)IO_(6))_(3)(DAI-X1).这些化合物具有立方钙钛矿结构,不仅具有高碘含量(49–54wt%),而且具有较高的爆速(6.331–6.558 km s^(-1))和爆压(30.69–30.88 GPa).特别地,DAI-4具有高达54.0 wt%的碘含量,以及6.558 km s^(-1)的爆速.激光扫描共聚焦显微镜观察和标准微量肉汤稀释法实验表明,DAI-4的爆炸产物对细菌(大肠杆菌、金黄色葡萄球菌和铜绿假单胞菌)具有广谱杀菌性.这类基于高碘酸根的分子钙钛矿具有易于放大合成、低成本、高爆轰性能和高碘含量的优点,是极具潜力的新型含能杀菌剂.

Epidemics caused by pathogens in recent years have created an urgent need for energetic biocidal agents with the capacity of detonation and releasing bactericides.Herein we present a new type of energetic biocidal agents based on a series of iodine-rich molecular perovskites,(H_(2)dabco)M(IO_(4))_(3)(dabco=1,4-diazabicyclo[2.2.2]octane,M=Na^(+)/K^(+)/Rb^(+)/NH_(4)^(+)for DAI-1/2/3/4)and(H_(2)dabco)Na(H_(4)IO_(6))_(3)(DAI-X1).These compounds possess a cubic perovskite structure,and notably have not only high iodine contents(49–54 wt%),but also high performance in detonation velocity(6.331–6.558 km s-1)and detonation pressure(30.69–30.88 GPa).In particular,DAI-4 has a very high iodine content of 54.0 wt%and simultaneously an exceptional detonation velocity up to 6.558 km s^(-1).As disclosed by laser scanning confocal microscopy observation and a standard micro-broth dilution method,the detonation products of DAI-4 exhibit a broad-spectrum bactericidal effect against bacteria(E.coli,S.aureus,and P.aeruginosa).The advantages of easy scale-up synthesis,low cost,high detonation performance,and high iodine contents enable these periodate-based molecular perovskites to be highly promising candidates for energetic biocidal agents.