骨质疏松性骨折临床管理研究热点及现状的可视化文献计量分析

Bibliometrics and visualized analysis of research hotspots and current status in clinical management of osteoporotic fractures

目的基于Web of Science数据库,利用文献计量学和可视化分析探究骨质疏松性骨折临床管理领域的各国研究现状、热点和发展趋势。方法收集Web of Science数据库收录的骨质疏松性骨折临床管理文献,应用文献计量学分析文献出版年、国家、机构、期刊、作者、高被引文献及研究热点,利用VOSviewer软件绘制可视化视图。结果分析收集的2508篇文献,可呈现三类结果。(1)文献基础信息分析显示:①发文量最多的国家是美国(672篇),其次是英国和加拿大,中国位居第四;②发文量前三的作者分别是Kanis JA、Cooper C和McCloskey EV;③发文量最多的机构是英国谢菲尔德大学,其次是英国南安普敦大学和加拿大多伦多大学。(2)文献高被引聚类分析显示,118篇高被引文献主要分为五大聚类,涉及骨质疏松性骨折诊断、治疗、药物依从性、管理共识及预防再骨折策略。(3)研究热点时间叠加视图显示,早期研究主要集中在传统治疗药物,当前研究热点主要为分子靶向药物、骨小梁评分和骨折联络服务。结论本研究分析说明:在全球范围内骨质疏松性骨折临床管理的研究活跃度日益增加,我国与欧美国家相比仍存在较大差距。当前的研究热点和发展趋势主要关注于分子靶向药物、骨质疏松性骨折治疗理念、新兴骨折风险评估工具和骨折防治管理模式。

Objective Based on Web of Science database,this study aimed to explore the current status,research hotspots and development trends of countries regarding clinical management of osteoporotic fractures using bibliometrics and visualized analysis.Methods We collected literatures in the field of clinical management of osteoporotic fractures included in Web of Science database,and applied bibliometrics to analyze the publication dates,countries,institutions,journals,authors,highly cited literatures and research hotspots.Visualization was drawn by VOSviewer software.Results Analysis of the 2508 articles revealed 3 types of data.(1)The analysis of basic information of the literature showed that:①The country with the largest number of publications was the United States,which published 672 articles,followed by the United Kingdom and Canada,and China ranked fourth;②The top three authors in the number of publications were Kanis JA,Cooper C and McCloskey EV respectively;③The institution with the highest number of publications was the University of Sheffield,UK,followed by the University of Southampton,UK and the University of Toronto,Canada.(2)Network visualization of highly cited literatures showed that 118 highly cited literatures were mainly divided into 5 clusters,which were related to osteoporotic fracture diagnosis,treatment,medication adherence,management consensus and strategies of preventing refracture.(3)Temporal overlay visualization of research hotspots showed that early research mainly focused on traditional therapeutic drugs,and current research hotspots were mainly molecular targeted drugs,trabecular bone score and fracture liaison services.Conclusion This study shows that the research activity of clinical management of osteoporotic fractures is increasing worldwide,and there is still a huge gap between China and Europe or the United States.Current research hotspots and development trends mainly focus on molecular targeted drugs,osteoporotic fracture treatment concepts,emerging fracture risk assessment tools,and fracture prevention and management models.