硅酸钙类骨水泥改性研究进展

Research progress on modification of calcium silicate bone cement

硅酸钙类骨水泥材料具有良好的自固化性能,能够作为硬组织修复材料对缺损的骨和牙进行填充和修复,但是由于其力学性能不足、固化时间长等缺点限制了其在临床上的应用范围。该文主要综述了硅酸钙粉体的制备方法及硅酸钙类骨水泥的力学强度、凝结时间、可注射性、降解及生物相容性等,并提出今后的研究重点是利用各体系骨水泥间的性能互补关系,将硅酸钙类骨水泥与其他体系骨水泥进行交叉复合,有望获得综合性能优良的无机复合骨水泥。

Calcium silicate bone cement materials are suitable for hard tissue repair to fill and repair the bone and teeth defects due to their good self-curing properties.However,their clinical applications are limited by their low mechanical properties,long curing time and other shortcomings.In this review,the preparation methods of calcium silicate powder as well as the mechanical strength,setting time,injectability,degradation and biocompatibility of calcium silicate bone cement were discussed.Moreover,It was suggested that future research directions should focus on synthesis of inorganic composite bone cement with excellent comprehensive properties by cross-coupling calcium silicate cement with cement of other systems based on their complementary performances.