摘要
以苦参碱为原料,通过水解内酰胺、甲酯化、还原、酯化4步反应合成了27个苦参碱的衍生物;松材线虫(Bursaphelenchu xylophilus)的室内杀虫活性测试表明,这些合成的化合物对松材线虫有一定的杀虫作用.研究结果可为苦参碱衍生物杀虫活性的进一步研究提供数据参考.
Starting from matrine,twenty-seven matrine derivatives were synthesized through subsequent hydrolysis,methyl esterification,reduction,and re-esterification.The investigation of their insecticidal activity showed that these synthetic compounds had insecticidal effect against bursaphelenchu xylophilus.The results can provide data support for the further studies of the insecticidal activity of matrine-type derivatives.
作者
寇明泽
展惠英
KOU Ming-ze;ZHAN Hui-ying(School of Chemical Engineering,Lanzhou University of Arts and Science,Lanzhou 730000,China)
出处
《兰州文理学院学报（自然科学版）》
2023年第2期83-88,共6页
Journal of Lanzhou University of Arts and Science(Natural Sciences)
基金
兰州市科技局项目(2020-RC-128)。
关键词
苦参碱
苦参碱衍生物
半合成
松材线虫
matrine
derivatives of matrine
semisynthesis
bursaphelenchu xylophilus
