摘要
目的:探究磁共振单体素波谱序列(MRS)在中老年人群多裂肌退变定量评估中的应用价值,并分析其与健康相关生活质量的关系。方法:公开招募109例中老年受试者作为研究对象,借助MRS序列定量分析受试者多裂肌退变情况,评价指标包括:脂肪分数(FF)、水脂比(W/F)、脂肪不对称程度(FAD)。同时,所有受试者均在安静状态下填写疼痛视觉模拟评分(VAS)、功能障碍指数(ODI)、Roland-Morris腰痛功能障碍评分(RMQ)以及36项简易健康问卷评分量表(SF-36),分析两者之间的相关性。结果:多裂肌FF与VAS、ODI、RMQ呈正相关,与SF-36总分呈负相关(P<0.05);多裂肌W/F与VAS、ODI、RMQ呈负相关,与SF-36总分呈正相关(P<0.05)。结论:多裂肌FF及W/F与中老年人群健康相关生活质量密切相关,可能是反映中老年患者下腰痛、功能障碍情况及健康相关生活质量的敏感指标。
Objective:To investigate the utility of magnetic resonance spectroscopy(MRS)for quantitative assessment of lumbar multifidus muscle degeneration and its association with health-related quality of life in middle-aged and elderly individuals.Methods:This study recruited 109 middle-aged and elderly individuals and conducted an MRS-based quantitative analysis of lumbar multifidus muscle degeneration using fat fraction(FF),water-to-fat ratio(W/F),fat asymmetry degree(FAD).In addition,visual analog scale(VAS),the Oswestry Disability Index(ODI),the Roland-Morris Questionnaire(RMQ),and the 36-Item Short Form Health Survey(SF-36)were constructed to survey health status in resting state for all individuals.Correlations between lumbar multifidus muscle degeneration and health-related quality of life were analyzed.Results:The FF of lumbar multifidus muscle was positively correlated with the VAS,ODI,and RMQ scores and negatively correlated with the SF-36 score(all P<0.05).Conversely,the W/F of lumbar multifidus muscle was negatively correlated with the VAS,ODI,and RMQ scores and displayed a positive correlation with the SF-36 score(all P<0.05).Conclusion:The FF and W/F of lumbar multifidus muscle are closely associated with the health-related quality of life of middle-aged and elderly populations and thus may serve as sensitive predictors of low back pain,dysfunctional conditions,and health-related quality of life in middle-aged and elderly patients.
作者
陈灿
陈品珍
赵骏
张承旻
杨森
喻学科
陈春华
李凯
张曌
罗飞
CHEN Can;CHEN Pinzhen;ZHAO Jun;ZHANG Chengmin;YANG Sen;YU Xueke;CHEN Chunhua;LI Kai;ZHANG Zhao;LUO Fei(Department of Orthopaedics,the First Affiliated Hospital,Army Medical University/The third Military Medical University,Chongqing 400038,China;Department of Radiology,the First Affiliated Hospital,Army Medical University/The third Military Medical University,Chongqing 400038,China;Department of Combat Casualty Care Training,Army Training Base for Health Care,Army Medical University/The third Military Medical University,Chongqing 400038,China;Department of Orthopaedics,the 83rd Army Hospital of the PLA,Xinxiang 453000,Henan,China)
出处
《暨南大学学报(自然科学与医学版)》
CAS
北大核心
2023年第1期23-29,共7页
Journal of Jinan University(Natural Science & Medicine Edition)
基金
重庆市技术创新与应用发展专项项目(cstc2019jscx-msxmX0221)
重庆市科卫联合医学科研项目(2023ZDXM018)
军队后勤科研重大项目(AWS17J004)。
关键词
多裂肌
磁共振单体素波谱
健康相关生活质量
lumbar multifidus muscle
magnetic resonance spectroscopy
health-related quality of life