鲍曼不动杆菌生物被膜防治进展

Advances in the prevention and treatment of Acinetobacter baumannii biofilms

鲍曼不动杆菌是一种全球耐药机会性革兰阴性细菌,常引起生物被膜相关感染。鲍曼不动杆菌极易黏附在导管等医疗植入物和生物表面,形成生物被膜。由于生物被膜的存在,导致了鲍曼不动杆菌不易被清除,是导致鲍曼不动杆菌泛耐药或多重耐药的原因之一。因此,目前亟需开发预防和治疗鲍曼不动杆菌生物被膜的新方法。本文就近几年鲍曼不动杆菌生物被膜的预防和治疗作一综述,以期为鲍曼不动杆菌生物被膜相关感染的防治提供新思路。

Acinetobacter baumannii is a globally drug-resistant opportunistic Gram-negative bacterium that frequently causes biofilm-associated infections.Acinetobacter baumannii can easily adhere to medical implants and biological surfaces such as catheters to form biofilms.Due to the existence of biofilm,the removal of Acinetobacter baumannii is particularly difficult.Therefore,there is an urgent need to develop new methods to prevent and treat Acinetobacter baumannii biofilm.This article reviews the prevention and treatment of Acinetobacter baumannii biofilm infection in recent years,in order to provide new ideas for biofilm prevention and treatment of Acinetobacter baumannii.