银黄二陈合剂黄芩苷提取转移率工艺研究

Study on the Extraction and Transfer Rate of Baicalin from Yinhuang Erchen Compound

通过考察黄芩苷转移率,改进和完善银黄二陈合剂提取工艺,进一步提高银黄二陈合剂中黄芩苷的含量。结果显示,在提取溶媒中加入不同量的pH调节剂枸椽酸钠,可以有效增加黄芩苷在水中的溶解度,其中添加0.20%枸椽酸钠效果较好,可以提高黄芩苷的转移率10%以上,为含黄芩制剂产品的质量控制提供了可靠的研究基础。

By investigating the transfer rate of baicalin,the extraction process of Yinhuang erchen compound was improved and perfected,and the content of baicalin in Yinhuang erchen compound was further increased.The results showed that adding different amounts of pH regulator sodium citrate could effectively increase the solubility of baicalin in water,and adding 0.20%sodium citrate was the best,which could improve the transfer rate of baicalin by more than 10%,providing a reliable research basis for the quality control of baicalin preparation products.