膝关节炎患者关节腔药物注射方案标准化现状及评价

Current Situation and Evaluation of Standardization of Intra-articular Drug Injection Scheme for Patients with Knee Osteoarthritis

膝关节骨性关节炎是一种退行性病变疾病,会造成巨大的社会和经济负担。作为一种涉及代谢、遗传和生物力学因素的进展性复杂疾病,目前尚无治疗KOA的统一标准化诊疗指南。关节腔内药物注射作为保守治疗的重要手段,具有很大的发展前景,如何促进关节腔药物注射方案标准化及规范化的形成是目前需要解决的关键问题。现就关节腔内药物注射治疗方案应用情况、标准化现状及依据指南对药物治疗作用的评价进行文献综述。

Osteoarthritis of knee is a degenerative disease,which has caused huge social and economic burden.As a progressive complex disease involving metabolic,genetic and biomechanical factors,there is no unified standardized diagnosis and treatment guideline for KOA.Intra-articular drug injection,as an important means of conservative treatment,has a great prospect.This article reviews the application and standardization of intra-articular drug injection therapy and the evaluation of drug therapy according to the guidelines.