烟雾病脑网络改变的研究进展

Research progress of brain network changes in moyamoya disease

烟雾病是一种原因不明的进展性脑血管阻塞性疾病,认知功能损害是其常见伴随症状,严重降低了患者的生活质量。作为一种新兴的分析技术,脑网络从宏观上研究大脑各区域间的交互,对于深入了解大脑结构和功能、探索大脑疾病的发生发展机制和评估诊疗方法有重要作用。同时,脑网络分析也为探索烟雾病的认知损伤机制以及认知损伤的诊断、治疗和预后评估提供了重要手段。现就烟雾病认知损伤相关脑网络的研究进行综述。

Moyamoya disease(MMD)is a progressive cerebrovascular obstructive disorder with unknown causes.Cognitive impairment is a common concomitant symptom of MMD,which seriously reduces the quality of life.As a new analysis technology,brain network aims to study the interaction of various regions of the brain macroscopically,which plays an important role in deeply understanding the brain structure and function,exploring the occurrence and progression mechanism and evaluating diagnosis and treatment of brain diseases.Meanwhile,brain network also provides an important method for exploring the mechanism of cognitive impairment of MMD and the diagnosis,treatment and prognosis evaluation of cognitive impairment.This paper reviews the research on cognitive impairment related brain networks of MMD.