早期肠内营养对慢性阻塞性肺疾病急性加重期患者血清营养指标及生活质量的影响

Effects of Early Enteral Nutrition on Serum Nutritional Indexes and Quality of Life in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的:探讨早期肠内营养对慢性阻塞性肺疾病急性加重期患者血清营养指标及生活质量的影响。方法:收集2020年10月—2022年2月在我院就诊的60例慢性阻塞性肺疾病急性加重期患者为研究对象,按照随机数字表将患者均分为常规营养治疗组(对照组)和早期肠内营养治疗组(观察组)。比较住院当天和营养治疗14 d后血清总蛋白(TP)、血清前白蛋白(PA)、血清白蛋白(ALB)、血红蛋白(HGB)水平变化,以及2组患者生活质量评分和并发症发生情况差异。结果:早期肠内营养治疗患者血清TP、PA、HGB、ALB下降水平均显著低于常规营养治疗组患者,且早期肠内营养治疗组患者躯体状态、心理功能、社会功能和物质功能评分比对照组患者更高,而腹胀腹泻、二重感染和血糖异常发生率则显著低于对照组患者(均有P<0.05)。结论:早期肠内营养可缓解慢性阻塞性肺疾病急性加重期患者血清营养指标的下降,改善患者生活质量,降低患者并发症发生率,可纳入临床治疗中。

Objective To investigate the effect of early enteral nutrition on serum nutritional indexes and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease.Method A total of 60 patients with acute exacerbation of chronic obstructive pulmonary disease who were treated in our hospital from October 2020 to February 2022 were collected as research objects.According to the random number table,the patients were equally divided into a conventional nutrition therapy group(control group)and an early enteral nutrition therapy group(observation group).The changes of serum total protein(TP),serum prealbumin(PA),serum albumin(ALB),and hemoglobin(HGB)levels on the day of hospitalization and after 14 days of nutritional treatment,as well as the differences in quality of life scores and complications between the two groups were compared.Result The decreased levels of serum TP,PA,HGB and ALB in patients with early enteral nutrition treatment were significantly lower than those in the conventional nutrition treatment group.The scores of physical status,psychological function,social function and material function of the patients in the early enteral nutrition treatment group were higher than those of the control group,while the incidence of abdominal distension,diarrhea,superinfection and abnormal blood sugar were significantly lower than those of the control group(all have P<0.05).Conclusion Early enteral nutrition can alleviate the decline of serum nutritional indicators in patients with acute exacerbation of chronic obstructive pulmonary disease,improve the quality of life of patients,and reduce the incidence of complications in patients,and can be included in clinical treatment.